Developmental regulation of human truncated nerve growth factor receptor

• Published in: Annals of neurology Vol. 29; no. 1; p. 13
• Main Authors: DiStefano, P S, Clagett-Dame, M, Chelsea, D M, Loy, R
• Format: Journal Article
• Language: English
• Published: United States 01.01.1991
• Subjects: Adolescent; Adult; Aged; Aging - metabolism; Antibodies, Monoclonal; Autoradiography; Biomarkers; Child; Child, Preschool; Humans; Immunoradiometric Assay - methods; Infant; Infant, Newborn; Kinetics; Middle Aged; Nerve Growth Factors - metabolism; Peripheral Nerves - growth & development; Precipitin Tests; Receptors, Cell Surface - urine; Receptors, Nerve Growth Factor; Serum Albumin, Radio-Iodinated
• ISSN: 0364-5134
• DOI: 10.1002/ana.410290105

Monoclonal antibodies (designated XIF1 and IIIG5) recognizing distinct epitopes of the human truncated nerve growth factor receptor (NGF-Rt) were used in a two-site radiometric immunosorbent assay to monitor levels of NGF-Rt in human urine as a function of age. Urine samples were collected from 70 n...