Coupling of salting-out assisted liquid–liquid extraction with on-line stacking for the analysis of tyrosine kinase inhibitors in human plasma by capillary zone electrophoresis - Ahmed, Omar S.; Ladner, Yoann; Montels, Jérôme; Philibert, Laurent; Perrin, Catherine (Journal of Chromatography A, 2018)
Keywords: acetonitrile; Acetonitriles - chemistry; antineoplastic agents; Blood Chemical Analysis - methods; Capillary electrophoresis; capillary zone electrophoresis; Centrifugation; chemical species; chromatography; Electrophoresis, Capillary; enzyme inhibitors; Enzyme Inhibitors - blood; Enzyme Inhibitors - metabolism; Humans; Life Sciences; Liquid-Liquid Extraction; monitoring; On-line CE stacking; patients; Plasma - chemistry; Protein-Tyrosine Kinases - antagonists & inhibitors; proteins; Salting-out assisted liquid–liquid extraction (SALLE); sodium chloride; Sodium Chloride - chemistry; statistical analysis; therapeutics; tyrosine; Tyrosine Kinase Inhibitor (TKI); BGE; CE; LLE; Capillary electrophoresis; SALLE; I; On-line CE stacking; TDM; Salting-out assisted liquid–liquid extraction (SALLE); Tyrosine Kinase Inhibitor (TKI)