Effects of selective cyclooxygenase isoform inhibition on systemic prostacyclin synthesis and on platelet function at rest and after exercise in healthy volunteers - Weber, Artur-Aron; Heim, Hans-Karl; Schumacher, Marc; Schrör, Karsten; Hohlfeld, Thomas (Platelets (Edinburgh), 2007)
Keywords: Adenosine Diphosphate - administration & dosage; Adult; Aspirin - administration & dosage; Aspirin - adverse effects; Atherosclerosis - complications; Atherosclerosis - enzymology; Cyclooxygenase 1 - metabolism; Cyclooxygenase 2 - metabolism; Cyclooxygenase 2 Inhibitors - administration & dosage; Cyclooxygenase 2 Inhibitors - adverse effects; Cycloxygenase; Double-Blind Method; Endothelium - enzymology; Epoprostenol - blood; Exercise; Humans; Isoenzymes - antagonists & inhibitors; Isoenzymes - metabolism; Lactones - administration & dosage; Lactones - adverse effects; Male; Platelet Activation - drug effects; platelets; prostacyclin; Rest; Risk Factors; Sulfones - administration & dosage; Sulfones - adverse effects; Thrombosis - enzymology; Thrombosis - etiology; thromboxane A; Thromboxane B2 - blood