On-chip pressure measurements and channel deformation after oil absorption

• Published in: SN applied sciences Vol. 2; no. 9; pp. 1501 - 8
• Main Authors: Hunter, Liam, Gala de Pablo, Julia, Stammers, Ashley C., Thomson, Neil H., Evans, Stephen D., Shim, Jung-uk
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.09.2020; Springer Nature B.V; Springer
• Subjects: 6. Interdisciplinary (general); Absorption; Applied and Technical Physics; Atomic force microscopy; Blood vessels; Channel deformation; Channels; Chemistry/Food Science; Deformation; Diffusion; Diffusion coefficient; Earth Sciences; Engineering; Environment; Flow profiles; Flow velocity; Fluorescence microscopy; Geometry; Infiltration; Internal pressure; Materials Science; Measurement methods; Mechanical properties; Microfluidics; Microscopy; Mineral oils; Modulus of elasticity; Nanoindentation; Polydimethylsiloxane; Polymers; Pressure; Pressure drop; Pressure measurement; Raman spectroscopy; Research Article; Silicon wafers; Channel deformation; Diffusion; Pressure drop; Nanoindentation

Microfluidic channels moulded from the soft polymer poly(dimethylsiloxane) (PDMS) are widely used as a platform for mimicking biological environments, and can be used for the simulation of fluid filled structures such as blood and lung vessels. The control of pressure and flow rate within these stru...