Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions - Thiele, Michael; Kerschbaumer, Randolf J; Tam, Frederick W K; Völkel, Dirk; Douillard, Patrice; Schinagl, Alexander; Kühnel, Harald; Smith, Jennifer; McDaid, John P; Bhangal, Gurjeet; Yu, Mei-Ching; Pusey, Charles D; et al. (The Journal of immunology (1950), 2015)
Keywords: Animals; Antibodies, Monoclonal - immunology; Antibodies, Monoclonal - therapeutic use; Blotting, Western; Dexamethasone - immunology; Dexamethasone - therapeutic use; Disease Models, Animal; Enterocolitis - immunology; Enterocolitis - metabolism; Enterocolitis - prevention & control; Flow Cytometry; Glomerulonephritis - immunology; Glomerulonephritis - metabolism; Glomerulonephritis - prevention & control; Glucocorticoids - immunology; Glucocorticoids - therapeutic use; Humans; Inflammation - immunology; Inflammation - metabolism; Inflammation - prevention & control; Innate Immunity and Inflammation; Macrophage Migration-Inhibitory Factors - chemistry; Macrophage Migration-Inhibitory Factors - immunology; Macrophage Migration-Inhibitory Factors - metabolism; Male; Mice, Inbred C57BL; Mice, Knockout; Molecular Targeted Therapy - methods; Oxidation-Reduction; Protein Conformation; Protein Isoforms - chemistry; Protein Isoforms - immunology; Protein Isoforms - metabolism; Rabbits; Rats, Inbred WKY