The effect of metformin on mean platelet volume in dıabetıc patients

• Published in: Platelets (Edinburgh) Vol. 24; no. 2; pp. 118 - 121
• Main Authors: Dolasık, Ilhan, Sener, Selcuk Y., Celebı, Koray, Aydın, Zekı M., Korkmaz, Ugur, Canturk, Zeynep
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01.01.2013
• Subjects: Adult; atherosclerosis; Blood Platelets - drug effects; Case-Control Studies; Diabetes mellitus; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - drug therapy; Female; Humans; Hypoglycemic Agents - pharmacology; Hypoglycemic Agents - therapeutic use; Male; mean platelet volume; metformin; Metformin - pharmacology; Metformin - therapeutic use; Middle Aged; platelet; Platelet Count

Diabetes mellitus (DM) is an independent risk factor for cardiovascular diseases. Metformin, the most commonly used antidiabetic, also has an antiatherogenic effect. Mean platelet volume (MPV) is increased in patients with high thrombogenic activation and also at risk for atherosclerosis. The purpos...