Recent progress of C-glycosylation methods in the total synthesis of natural products and pharmaceuticals

• Published in: Organic & biomolecular chemistry Vol. 16; no. 11; pp. 1791 - 186
• Main Authors: Liao, Hongze, Ma, Jimei, Yao, Hui, Liu, Xue-Wei
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 2018
• Subjects: Biological activity; Biological Products - chemical synthesis; Biological Products - chemistry; Chemical synthesis; Chemistry Techniques, Synthetic - methods; Cyclic compounds; Glycosides; Glycosides - chemical synthesis; Glycosides - chemistry; Glycosylation; Hydrocarbons, Acyclic - chemical synthesis; Hydrocarbons, Acyclic - chemistry; Hydrocarbons, Cyclic - chemical synthesis; Hydrocarbons, Cyclic - chemistry; Natural products; Pharmaceutical Preparations - chemical synthesis; Pharmaceutical Preparations - chemistry; Pharmaceuticals; Stereoisomerism; Stereoselectivity

Chemical C -glycosylation has been well developed to improve stereoselectivity in recent years. Due to its high efficiency to build C -glycosides or O -cyclic compounds, C -glycosylation has found widespread use in the synthesis of biologically active molecules. This review highlights the C -glycosy...