Short chain fatty acids: Microbial metabolites for gut-brain axis signalling

• Published in: Molecular and cellular endocrinology Vol. 546; p. 111572
• Main Authors: O'Riordan, Kenneth J., Collins, Michael K., Moloney, Gerard M., Knox, Emily G., Aburto, María R., Fülling, Christine, Morley, Shane J., Clarke, Gerard, Schellekens, Harriët, Cryan, John F.
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 15.04.2022
• Subjects: acetates; Bacteria; blood-brain barrier; brain; Brain-Gut Axis; butyrates; dietary fiber; digestive system; endocrinology; Fatty Acids, Volatile - metabolism; fermentation; Gastrointestinal Microbiome; intestinal microorganisms; metabolites; Microbiome; Microbiota; Microbiota-gut-brain axis; propionic acid; Short-chain fatty acids; Signal Transduction; therapeutics; Short-chain fatty acids; Microbiota-gut-brain axis; Microbiota; Microbiome

The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to prominence in recent years. Understanding the relationship between the gut microbiota, the metabolites it produces, and the brain will be critical for the subsequent development of new therapeutic approach...