Dimethyl Sulfoxide Suppresses Mouse 4T1 Breast Cancer Growth by Modulating Tumor-Associated Macrophage Differentiation

• Published in: Journal of breast cancer Vol. 17; no. 1; pp. 25 - 32
• Main Authors: Deng, Rui, Wang, Shi-Min, Yin, Tao, Ye, Ting-Hong, Shen, Guo-Bo, Li, Ling, Zhao, Jing-Yi, Sang, Ya-Xiong, Duan, Xiao-Gang, Wei, Yu-Quan
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Breast Cancer Society 01.03.2014; 한국유방암학회
• Subjects: Original; 일반외과학; Breast neoplasms; Dimethyl sulfoxide; Macrophage

The universal organic solvent dimethyl sulfoxide (DMSO) can be used as a differentiation inducer of many cancer cells and has been widely used as a solvent in laboratories. However, its effects on breast cancer cells are not well understood. The aim of this study is to investigate the effect and ass...