The micronucleus assay as a biological dosimeter in hospital workers exposed to low doses of ionizing radiation

• Published in: Mutation research Vol. 747; no. 1; pp. 7 - 13
• Main Authors: Ropolo, Monica, Balia, Cristina, Roggieri, Paola, Lodi, Vittorio, Nucci, Maria Concetta, Violante, Francesco Saverio, Silingardi, Paola, Colacci, Annamaria, Bolognesi, Claudia
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 30.08.2012; Elsevier BV
• Subjects: Adult; Bio-dosimetry; Bioassays; Cytogenetics; Dosimetry; Female; Gamma rays; Gamma Rays - adverse effects; Health risks; Hospital staff; Hospitals; Human exposure; Humans; Hypersensitivity; Ionizing radiation; Low-dose radiation; Male; Manganese; Medical personnel; Micronuclei; Micronucleus test; Micronucleus Tests - methods; Middle Aged; Mutagenesis; Occupational exposure; Occupational Exposure - adverse effects; Personnel, Hospital; Radiation; Radiation Dosage; Radiation, Ionizing; Radiometry; Risk factors; Sex; Smoking; X-Rays - adverse effects; Bio-dosimetry; Ionizing radiation; Micronucleus test; Low-dose radiation; Hospital staff; Occupational exposure

The health risk associated with low levels of ionizing radiation is still a matter of debate. A number of factors, such as non-target effects, adaptive responses and low-dose hypersensitivity, affect the long-term outcome of low-dose exposures. Cytogenetic bio-dosimetry provides a measure of the abs...