Cancer blues? A promising judgment bias task indicates pessimism in nude mice with tumors

• Published in: Physiology & behavior Vol. 238; p. 113465
• Main Authors: Resasco, A., MacLellan, A., Ayala, M.A., Kitchenham, L., Edwards, A.M., Lam, S., Dejardin, S., Mason, G.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.09.2021
• Subjects: adenocarcinoma; Affective state; Animal welfare; behavior; biomedical research; Cancer; females; Judgment bias; Laboratory mice; lungs; males; mice; physiology; Validation; Judgment bias; Validation; Laboratory mice; Affective state; Animal welfare; Cancer

•We present a novel judgment bias task to assess affective state in mice.•Environmentally enriched housing was used to manipulate mouse affective state.•Enriched mice responded to ambiguity with relative optimism, validating the task.•The task was also used to assess judgment bias in tumor-bearing n...