C-reactive protein binds to Fc gamma RI in transfected COS cells

• Published in: The Journal of immunology (1950) Vol. 155; no. 4; pp. 2185 - 2193
• Main Authors: Marnell, LL, Mold, C, Volzer, MA, Burlingame, RW, Du Clos, TW
• Format: Journal Article
• Language: English
• Published: United States Am Assoc Immnol 15.08.1995
• Subjects: Amino Acid Sequence; Antibody Affinity; C-Reactive Protein - metabolism; Cells, Cultured; Humans; Immunoglobulin G - metabolism; Molecular Sequence Data; Receptors, IgG - metabolism; Transfection

C-Reactive protein (CRP) is an acute phase serum protein in man that binds to certain bacterial polysaccharides and to components exposed on damaged cells. CRP is bound by receptors on phagocytic cells and functions as an opsonin for its ligands. Interactions of CRP with a specific CRP receptor (CRP...