MptpA Kinetics Enhanced by Allosteric Control of an Active Conformation - Maschietto, Federica; Zavala, Erik; Allen, Brandon; Loria, J. Patrick; Batista, Victor (Journal of molecular biology, 2022)
Keywords: active sites; Allosteric Regulation; allostery; aspartic acid; Bacterial Proteins - chemistry; Catalytic Domain; enzymes; hydrolysis; Kinetics; leucine; molecular biology; molecular dynamics; molecular weight; mutants; mutation; Mycobacterium tuberculosis; Mycobacterium tuberculosis - enzymology; NMR spectroscopy; nuclear magnetic resonance spectroscopy; Protein Tyrosine Phosphatases - chemistry; protein-tyrosine-phosphatase; reaction kinetics; tuberculosis; enzymes; molecular dynamics; NMR spectroscopy; tuberculosis; allostery