Universal expression of cell adhesion molecule NCAM in neuroblastoma in contrast to L1: implications for different roles in tumor biology of neuroblastoma?

• Published in: Pediatric surgery international Vol. 24; no. 12; pp. 1361 - 1364
• Main Authors: Wachowiak, Robin, Rawnaq, Tamina, Metzger, Roman, Quaas, Alexander, Fiegel, Henning, Kähler, Nils, Rolle, Udo, Izbicki, Jakob R., Kaifi, Jussuf, Till, Holger
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.12.2008; Springer Nature B.V
• Subjects: Antigens, Neoplasm - metabolism; Biomarkers, Tumor - biosynthesis; CD56 Antigen - biosynthesis; Child, Preschool; Humans; Immunohistochemistry; Infant; Medicine; Medicine & Public Health; Neural Cell Adhesion Molecule L1 - biosynthesis; Neural Cell Adhesion Molecules - biosynthesis; Neuroblastoma - metabolism; Original Article; Pediatric Surgery; Pediatrics; Retrospective Studies; Surgery; Tissue Array Analysis; Immunhistochemistry; Neuroblastoma; NCAM; L1; CD56

Purpose Neuroblastoma is a biological, genetic and morphological heterogeneous tumor with a variable clinical course. NCAM is a cell adhesion molecule belonging to the immunoglobulin superfamily with structural similarities to cell adhesion molecule L1. The aim of this study was to determine the exp...