Safety of Human Embryonic Stem Cell-derived Mesenchymal Stem Cells for Treating Interstitial Cystitis: A Phase I Study

• Published in: Stem cells translational medicine Vol. 11; no. 10; pp. 1010 - 1020
• Main Authors: Shin, Jung Hyun, Ryu, Chae-Min, Yu, Hwan Yeul, Park, Juhyun, Kang, Ah Reum, Shin, Jeong Min, Hong, Ki-Sung, Kim, Eun Young, Chung, Hyung-Min, Shin, Dong-Myung, Choo, Myung-Soo
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 21.10.2022
• Subjects: Anesthesia; Cell therapy; Cystitis; Embryo cells; Human Clinical; Injection; Lesions; Mesenchymal stem cells; Pain; Patients; Stem cells; clinical trial; mesenchymal stem cell; embryonic stem cell; interstitial cystitis; Hunner lesion

Abstract There are still no definite treatment modalities for interstitial cystitis (IC). Meanwhile, stem cell therapy is rising as potential alternative for various chronic diseases. This study aimed to investigate the safety of the clinical-grade mesenchymal stem cells (MSCs) derived from human em...