Alternative dimerization interfaces in the glucocorticoid receptor-α ligand binding domain - Bianchetti, Laurent; Wassmer, Bianca; Defosset, Audrey; Smertina, Anna; Tiberti, Marion L.; Stote, Roland H.; Dejaegere, Annick (Biochimica et biophysica acta. General subjects, 2018)
Keywords: Animals; Binding free energy; Binding Sites; crystals; dimerization; DNA-binding domains; estrogens; germplasm conservation; Gibbs free energy; Glucocorticoid receptor; Homodimer; hormone receptors; Humans; Life Sciences; Ligand binding domain; Ligands; Mice; Models, Molecular; Molecular modeling; Protein Binding; Protein Conformation; Protein Domains; Protein Multimerization; Quantitative Methods; Receptors, Glucocorticoid - chemistry; Receptors, Glucocorticoid - metabolism; Sequence conservation; therapeutics; transcription factors; Homodimer; Binding free energy; Sequence conservation; Ligand binding domain; Molecular modeling; Glucocorticoid receptor