The association of electroconvulsive therapy to pharmacological treatment and its influence on cytokines

• Published in: Journal of psychiatric research Vol. 92; pp. 205 - 211
• Main Authors: Freire, Thiago Fernando Vasconcelos, PhD, Rocha, Neusa Sica da, PhD, Fleck, Marcelo Pio de Almeida, PhD
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.09.2017
• Subjects: Adult; Antidepressive Agents - therapeutic use; Cohort Studies; Combined Modality Therapy; Cytokines - blood; Depression; Depression - blood; Depression - therapy; ECT; Electroconvulsive Therapy - methods; Female; Humans; IFN-γ; IL-6; Immunology; Inpatients; Male; Middle Aged; Psychiatric Status Rating Scales; Psychiatry; Statistics, Nonparametric; TNF-α; Depression; IFN-γ; Immunology; TNF-α; IL-6; ECT

Abstract Introduction A growing body of evidence shows that disturbances in the immune system are involved in the pathogenesis of depression. Although the immune-modulating effects of antidepressants have been described, few studies have addressed the functioning of the immune system in relation to...