Influence of Betaxolol on the Methamphetamine Dependence in Mice

• Published in: Psychiatry investigation Vol. 13; no. 3; pp. 316 - 320
• Main Authors: Kim, Byoung-Jo, Park, Jong-Il, Eun, Hun-Jeong, Yang, Jong-Chul
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Neuropsychiatric Association 01.05.2016; 대한신경정신의학회
• Subjects: Original; 정신과학; Betaxolol; Conditioned place preference; Hyperactivity; Methamphetamine

The noradrenaline system is involved in the reward effects of various kinds of abused drugs. Betaxolol (BTX) is a highly selective β1-antagonist. In the present study, we evaluated the effect of BTX on methamphetamine (MAP)-induced conditioned place preference (CPP) and hyperactivity in mice. The mi...