Spatially resolved transcriptomics: a comprehensive review of their technological advances, applications, and challenges

• Published in: Journal of genetics and genomics Vol. 50; no. 9; pp. 625 - 640
• Main Authors: Cheng, Mengnan, Jiang, Yujia, Xu, Jiangshan, Mentis, Alexios-Fotios A., Wang, Shuai, Zheng, Huiwen, Sahu, Sunil Kumar, Liu, Longqi, Xu, Xun
• Format: Journal Article
• Language: English
• Published: China Elsevier Ltd 01.09.2023
• Subjects: Bioinformatic tools; bioinformatics; Cell communications; genomics; humans; Spatial single-cell; Spatially resolved transcriptomics; Three-dimensional organ; Tissue dissection; transcriptomics; Tissue dissection; Spatial single-cell; Three-dimensional organ; Spatially resolved transcriptomics; Bioinformatic tools; Cell communications

The ability to explore life kingdoms is largely driven by innovations and breakthroughs in technology, from the invention of the microscope 350 years ago to the recent emergence of single-cell sequencing, by which the scientific community has been able to visualize life at an unprecedented resolutio...