First experiences of photoacoustic imaging for detection of melanoma metastases in resected human lymph nodes

• Published in: Lasers in surgery and medicine Vol. 44; no. 7; pp. 541 - 549
• Main Authors: Grootendorst, D.J., Jose, J., Wouters, M.W., van Boven, H., Van der Hage, J., Van Leeuwen, T.G., Steenbergen, W., Manohar, S., Ruers, T.J.M.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.09.2012
• Subjects: Axilla; Biomarkers, Tumor - metabolism; Humans; Inguinal Canal; Intraoperative Care - methods; Lasers, Solid-State; lymph node; Lymph Node Excision; Lymphatic Metastasis - diagnosis; Melanins - metabolism; melanoma; Melanoma - metabolism; Melanoma - pathology; Melanoma - surgery; metastases; nodal metastases; optoacoustic; photoacoustic; Photoacoustic Techniques - methods; Skin Neoplasms - metabolism; Skin Neoplasms - pathology; Skin Neoplasms - surgery; Tomography

Background and Objective Excision and histological assessment of the first draining node (sentinel lymph node) is a frequently used method to assess metastatic lymph node involvement related to cutaneous melanoma. Due to the time required for accurate histological assessment, nodal status is not imm...