Markers of Bone Remodeling in Metastatic Bone Disease

• Published in: The journal of clinical endocrinology and metabolism Vol. 88; no. 11; pp. 5059 - 5075
• Main Authors: Fohr, Berthold, Dunstan, Colin R, Seibel, Markus J
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Endocrine Society 01.11.2003; Copyright by The Endocrine Society
• Subjects: Biological and medical sciences; Diseases of the osteoarticular system; Medical sciences; Miscellaneous. Osteoarticular involvement in other diseases; Antineoplastic agent; Chemotherapy; Biological marker; Bone disease; Malignant tumor; Diagnosis; Metastasis; Bone; Bone remodeling; Osseous tissue; Monitoring; Bibliographic review

Many cancers have a strong propensity to spread to bone. The processes involved in cancer dissemination to bone are complex and variable, and the changes in bone metabolism, once bony metastases have occurred, are usually profound. This review surveys the usefulness of bone markers in the diagnosis...