The chemistry and biological potential of azetidin-2-ones

• Published in: European journal of medicinal chemistry Vol. 74; pp. 619 - 656
• Main Authors: Arya, Nikhilesh, Jagdale, Archana Y., Patil, Tushar A., Yeramwar, Shradha S., Holikatti, Sidharam S., Dwivedi, Jaya, Shishoo, Chamanlal J., Jain, Kishor S.
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 03.03.2014
• Subjects: Anti-Infective Agents - chemical synthesis; Anti-Infective Agents - chemistry; Anti-Infective Agents - pharmacology; Azetidin-2-ones; Azetidines - chemical synthesis; Azetidines - chemistry; Azetidines - pharmacology; Bacteria - drug effects; Fungi - drug effects; Microbial Sensitivity Tests; Pharmacological profile; Synthesis; β-Lactam; Synthesis; β-Lactam; Azetidin-2-ones; Pharmacological profile

Azetidin-2-ones, commonly referred as β-lactams, represent a unique ring system, with interesting chemistry and great biological potential. Besides its well known antibiotic activity, this ring system exhibits a wide range of activities, attracting the attention of researchers. The biological and ph...