Development of novel benzamide class I selective lysine deacetylase inhibitors as potent anticancer agents - Gill, Jason H.; Sellars, Jonathan D.; Waddell, Paul G.; Shnyder, Steven D.; Grigg, Ronald; Fishwick, Colin W. G. (Journal of enzyme inhibition and medicinal chemistry, 2025)
Keywords: aminobenzamide; Animals; Antineoplastic Agents - chemical synthesis; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; Benzamides - chemical synthesis; Benzamides - chemistry; Benzamides - pharmacology; cancer chemotherapy; Cell Line, Tumor; Cell Proliferation - drug effects; Dose-Response Relationship, Drug; Drug Development; Drug Screening Assays, Antitumor; Female; HDAC Inhibitor; histone deacetylase (HDACs); Histone Deacetylase Inhibitors - chemical synthesis; Histone Deacetylase Inhibitors - chemistry; Histone Deacetylase Inhibitors - pharmacology; Histone Deacetylases - metabolism; Humans; Lysine Deacetylase (KDACs); Mice; Molecular Structure; protein acetylation; Structure-Activity Relationship; benzamide; Lysine Deacetylase (KDACs); cancer chemotherapy; protein acetylation; HDAC Inhibitor; histone deacetylase (HDACs); aminobenzamide