Mechanism of action of insecticidal secondary metabolites of plant origin
Insect pest management is facing the economic and ecological challenge worldwide due to the human and environmental hazards caused by majority of the synthetic pesticide chemicals. Identification of novel effective insecticidal compounds is essential to combat increasing resistance rates. Botanicals...
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| Published in | Crop protection Vol. 29; no. 9; pp. 913 - 920 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
Elsevier Ltd
01.09.2010
[Amsterdam]: Elsevier Science |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0261-2194 1873-6904 |
| DOI | 10.1016/j.cropro.2010.05.008 |
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| Abstract | Insect pest management is facing the economic and ecological challenge worldwide due to the human and environmental hazards caused by majority of the synthetic pesticide chemicals. Identification of novel effective insecticidal compounds is essential to combat increasing resistance rates. Botanicals containing active insecticidal phytochemicals appear to be promising to address some of these problems. Therefore, there is a continuous need to explore new active molecules with different mechanisms of action. Secondary metabolites present in plants apparently function as defense (toxic), which inhibits reproduction and other processes. The phytochemical biomolecules could be used for maximizing the effectiveness and specificity in future insecticide design with specific or multiple target sites, while ensuring the economic and ecological sustainability. In this article, the current state of knowledge on phytochemical sources and insecticidal activity, their mechanism of action in insects, resistance, and promising advances made in phytochemical research are reviewed. |
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| AbstractList | Insect pest management is facing the economic and ecological challenge worldwide due to the human and environmental hazards caused by majority of the synthetic pesticide chemicals. Identification of novel effective insecticidal compounds is essential to combat increasing resistance rates. Botanicals containing active insecticidal phytochemicals appear to be promising to address some of these problems. Therefore, there is a continuous need to explore new active molecules with different mechanisms of action. Secondary metabolites present in plants apparently function as defense (toxic), which inhibits reproduction and other processes. The phytochemical biomolecules could be used for maximizing the effectiveness and specificity in future insecticide design with specific or multiple target sites, while ensuring the economic and ecological sustainability. In this article, the current state of knowledge on phytochemical sources and insecticidal activity, their mechanism of action in insects, resistance, and promising advances made in phytochemical research are reviewed. |
| Author | Rattan, Rameshwar Singh |
| Author_xml | – sequence: 1 givenname: Rameshwar Singh surname: Rattan fullname: Rattan, Rameshwar Singh email: rsrattan@scientist.com organization: Entomology and Pesticide Residue Analysis Laboratory, Hill Area Tea Sciences (HATS) Division, Institute of Himalayan Bioresource Technology (CSIR), Post Box-6, Palampur 176061, Himachal Pradesh, India |
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| Keywords | Botanicals Plant allelochemicals Insecticide Toxicity Octopamine Insect pest management GABA Plant protection Acetylcholine Chemical ecology Mechanism of action |
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