Recent advances in the discovery, biosynthesis, and therapeutic potential of isocoumarins derived from fungi: a comprehensive update

• Published in: RSC advances Vol. 13; no. 12; pp. 849 - 889
• Main Authors: Tammam, Mohamed A, Gamal El-Din, Mariam I, Abood, Amira, El-Demerdash, Amr
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 08.03.2023; The Royal Society of Chemistry
• Subjects: Biosynthesis; Chemistry; Fungi; Metabolites; Microorganisms; Natural products; Pharmacology

Microorganisms still remain the main hotspots in the global drug discovery avenue. In particular, fungi are highly prolific producers of vast structurally diverse specialized secondary metabolites, which have displayed a myriad of biomedical potentials. Intriguingly, isocoumarins is one distinctive...