Evaluation of three physiologically based pharmacokinetic (PBPK) modeling tools for emergency risk assessment after acute dichloromethane exposure - Boerleider, R.Z.; Olie, J.D.N.; van Eijkeren, J.C.H.; Bos, P.M.J.; Hof, B.G.H.; de Vries, I.; Bessems, J.G.M.; Meulenbelt, J.; Hunault, C.C. (Toxicology letters, 2015)
Keywords: Acute exposure; Biomarkers - blood; Biotransformation; Blood; Bos; Carboxyhemoglobin; Carboxyhemoglobin - metabolism; Computer Simulation; Dichloromethane; Emergencies; Environmental Monitoring; Exposure; Healthy Volunteers; Humans; Inhalation Exposure; Intoxication; Mathematical models; Methylene Chloride - blood; Methylene Chloride - pharmacokinetics; Methylene Chloride - poisoning; Models, Biological; PBPK model; Poisoning; Risk Assessment; Risk Factors; Solvents - pharmacokinetics; Solvents - poisoning; Tissue Distribution; Young Adult; Dichloromethane; Poisoning; Acute exposure; Intoxication; Risk assessment; PBPK model