Sophoraflavanone G from Sophora alopecuroides inhibits lipopolysaccharide-induced inflammation in RAW264.7 cells by targeting PI3K/Akt, JAK/STAT and Nrf2/HO-1 pathways - Guo, Chao; Yang, Lei; Luo, Jun; Zhang, Chao; Xia, Yuanzheng; Ma, Ting; Kong, Lingyi (International immunopharmacology, 2016)
Keywords: Animals; Anti-Inflammatory Agents - pharmacology; Flavanones - pharmacology; Heme Oxygenase-1 - metabolism; Inflammation; Inflammation - drug therapy; Janus Kinases - metabolism; Lipopolysaccharides - immunology; LPS; Macrophages - drug effects; Macrophages - immunology; Membrane Proteins - metabolism; Mice; NF-E2-Related Factor 2 - metabolism; Phosphatidylinositol 3-Kinases - metabolism; Proto-Oncogene Proteins c-akt - metabolism; RAW 264.7 Cells; RAW264.7; Sophora - immunology; Sophoraflavanone G; STAT Transcription Factors - metabolism; NO; PGE2; COX-2; HO-1; Inflammation; IL-1β; LPS; IL-6; PIAS; NF-κB; STAT; SG; TNF-α; PI3K; Sophoraflavanone G; JAK; Nrf2; RAW264.7; Keap1; iNOS