A New Quantification Method Using Electrochemical Mass Spectrometry

• Published in: Journal of the American Society for Mass Spectrometry Vol. 30; no. 4; pp. 685 - 693
• Main Authors: Xu, Chang, Zheng, Qiuling, Zhao, Pengyi, Paterson, Joseph, Chen, Hao
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2019; Springer Nature B.V
• Subjects: Analytical Chemistry; Bioinformatics; Biotechnology; CALIBRATION; Chemistry; Chemistry and Materials Science; Dopamine; Electrochemical oxidation; ELECTROCHEMISTRY; ELECTROLYSIS; FARADAY LAWS; Glutathione; INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; Ions; ISOTOPES; LABELLED COMPOUNDS; Liquid chromatography; LIQUID COLUMN CHROMATOGRAPHY; Mass spectrometry; MASS SPECTROSCOPY; MEASURING METHODS; MOLECULES; Norepinephrine; Organic Chemistry; OXIDATION; Proteomics; Research Article; Scientific imaging; Spectroscopy; Uric acid; Urine; Electrochemistry; Quantification; Mass spectrometry; Chromatography

Mass spectrometry-based quantification method has advanced rapidly. In general, the methods for accurate quantification rely on the use of authentic target compounds or isotope-labeled compounds as standards, which might be not available or difficult to synthesize. To tackle this grand challenge, th...