Pleural mesothelioma classification—update and challenges

• Published in: Modern pathology Vol. 35; no. Suppl 1; pp. 51 - 56
• Main Author: Dacic, Sanja
• Format: Journal Article
• Language: English
• Published: New York Elsevier Inc 01.01.2022; Nature Publishing Group US; Elsevier Limited
• Subjects: 631/67/1641; 692/53/2421; Biomarkers, Tumor - genetics; Classification; Diagnosis; Diagnosis, Differential; Effusion; Gene deletion; Genes, p16; Humans; Immunohistochemistry; Laboratory Medicine; Long Course Article; Medicine; Medicine & Public Health; Mesothelioma; Mesothelioma, Malignant - diagnosis; Mesothelioma, Malignant - genetics; Mesothelioma, Malignant - pathology; Pathology; Pleura - pathology; Pleural Neoplasms - diagnosis; Pleural Neoplasms - genetics; Pleural Neoplasms - pathology; Prognosis; Tumor Suppressor Proteins - genetics; Tumors; Ubiquitin Thiolesterase - genetics
• ISSN: 0893-3952; 1530-0285; 1530-0285
• DOI: 10.1038/s41379-021-00895-7

Mesothelial tumors are classified into benign or preinvasive tumors, and mesotheliomas. The benign or preinvasive group includes adenomatoid tumors, well-differentiated papillary mesothelial tumors, and mesothelioma in situ. Malignant tumors are mesotheliomas and can be localized or diffuse. Histolo...