Association between epidermal growth factor receptor gene polymorphisms and susceptibility to Parkinson’s disease

• Published in: Neuroscience letters Vol. 736; p. 135273
• Main Authors: Jin, Jianing, Xue, Li, Bai, Xinling, Zhang, Xiaona, Tian, Qingwu, Xie, Anmu
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 25.09.2020
• Subjects: Age of Onset; Aged; Alleles; Case-Control Studies; EGFR; ErbB Receptors - genetics; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Male; Middle Aged; Parkinson Disease - genetics; Parkinson’s disease; PCR-RFLP; Polymorphism; Polymorphism, Single Nucleotide; PCR-RFLP; Parkinson’s disease; EGFR; Polymorphism

•This was the first study to identify the association between EGFR gene polymorphisms and susceptibility to PD.•The EGFR rs730437 and rs11506105 polymorphism was associated with susceptibility to PD in a Han Chinese population.•The subgroup analyses indicated that the C allele of rs730437 showed low...