Effect of herbal therapy to intensity chemotherapy-induced nausea and vomiting in cancer patients
Background : Chemotherapy-induced nausea and vomiting are the most important complications for cancer patients as its prevalence has been reported to be about 54-96 percent. Ginger has been used for medicinal purposes including nausea and vomiting in traditional Persian, Chinese and Indian pharmacop...
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Published in | Iranian red crescent medical journal Vol. 15; no. 2; pp. 101 - 106 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Dubai, United Arab Emirates
Iranian Hospital
01.02.2013
Zamen Salamati Publishing Kowsar |
Subjects | |
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Abstract | Background : Chemotherapy-induced nausea and vomiting are the most important complications for cancer patients as its prevalence has been reported to be about 54-96 percent. Ginger has been used for medicinal purposes including nausea and vomiting in traditional Persian, Chinese and Indian pharmacopoeia. Objectives : The objective of this study was to evaluate the efficacy of complimentary ginger among cancer patients experiencing nausea and vomiting. Material and Methods : A randomized cross-over clinical trial was carried out on patients under chemotherapy treatment for at least 2 episodes of chemotherapy and at least 2 episodes of previous experience of nausea and vomiting. Subjects of this study received 2 different complementary regimes with 250mg ginger capsule in regime A and placebo capsule in regime B. subjects of the study were crossed over to receive the other regime during the two cycles of chemotherapy. Results : Findings of the study indicated that subjects receiving ginger showed significant reduction in frequency and intensity of nausea and vomiting compared to placebo receiving subjects. Conclusions : According to finding of this study, in accordance to most of other researches, ginger is an effective agent to reduce chemotherapy induced nausea and vomiting. However, there are some researches supporting ginger as a moderate antiemetic agent among cancerous patients under chemotherapy. |
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AbstractList | Background : Chemotherapy-induced nausea and vomiting are the most important complications for cancer patients as its prevalence has been reported to be about 54-96 percent. Ginger has been used for medicinal purposes including nausea and vomiting in traditional Persian, Chinese and Indian pharmacopoeia. Objectives : The objective of this study was to evaluate the efficacy of complimentary ginger among cancer patients experiencing nausea and vomiting. Material and Methods : A randomized cross-over clinical trial was carried out on patients under chemotherapy treatment for at least 2 episodes of chemotherapy and at least 2 episodes of previous experience of nausea and vomiting. Subjects of this study received 2 different complementary regimes with 250mg ginger capsule in regime A and placebo capsule in regime B. subjects of the study were crossed over to receive the other regime during the two cycles of chemotherapy. Results : Findings of the study indicated that subjects receiving ginger showed significant reduction in frequency and intensity of nausea and vomiting compared to placebo receiving subjects. Conclusions : According to finding of this study, in accordance to most of other researches, ginger is an effective agent to reduce chemotherapy induced nausea and vomiting. However, there are some researches supporting ginger as a moderate antiemetic agent among cancerous patients under chemotherapy. Chemotherapy-induced nausea and vomiting are the most important complications for cancer patients as its prevalence has been reported to be about 54-96 percent. ginger has been used for medicinal purposes including nausea and vomiting in traditional Persian, Chinese and Indian pharmacopoeia. The objective of this study was to evaluate the efficacy of complimentary ginger among cancer patients experiencing nausea and vomiting. A randomized cross-over clinical trial was carried out on patients under chemotherapy treatment for at least 2 episodes of chemotherapy and at least 2 episodes of previous experience of nausea and vomiting. Subjects of this study received 2 different complementary regimes with 250mg ginger capsule in regime A and placebo capsule in regime B. subjects of the study were crossed over to receive the other regime during the two cycles of chemotherapy. Findings of the study indicated that subjects receiving ginger showed significant reduction in frequency and intensity of nausea and vomiting compared to placebo receiving subjects. According to finding of this study, in accordance to most of other researches, ginger is an effective agent to reduce chemotherapy-induced nausea and vomiting. However, there are some researches supporting ginger as a moderate antiemetic agent among cancerous patients under chemotherapy. BACKGROUNDChemotherapy-induced nausea and vomiting are the most important complications for cancer patients as its prevalence has been reported to be about 54-96 percent. ginger has been used for medicinal purposes including nausea and vomiting in traditional Persian, Chinese and Indian pharmacopoeia. OBJECTIVESThe objective of this study was to evaluate the efficacy of complimentary ginger among cancer patients experiencing nausea and vomiting. MATERIAL AND METHODSA randomized cross-over clinical trial was carried out on patients under chemotherapy treatment for at least 2 episodes of chemotherapy and at least 2 episodes of previous experience of nausea and vomiting. Subjects of this study received 2 different complementary regimes with 250mg ginger capsule in regime A and placebo capsule in regime B. subjects of the study were crossed over to receive the other regime during the two cycles of chemotherapy. RESULTSFindings of the study indicated that subjects receiving ginger showed significant reduction in frequency and intensity of nausea and vomiting compared to placebo receiving subjects. CONCLUSIONSAccording to finding of this study, in accordance to most of other researches, ginger is an effective agent to reduce chemotherapy-induced nausea and vomiting. However, there are some researches supporting ginger as a moderate antiemetic agent among cancerous patients under chemotherapy. |
Author | Muntazari, Azam Sadat Dadgari, Ali Qanbari, Atifah Rai, Mahdi Hamid Zadah, Azam Muntazari, Akram Sadat |
AuthorAffiliation | 2 Clinical Research Development Center, Qom University of Medical Sciences, Qom, IR Iran 4 School of Pharmacy, Tehran University of Medical Sciences, Tehran, IR Iran 3 School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, IR Iran 1 School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, IR Iran |
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Cites_doi | 10.1007/s00520-003-0482-4 10.1016/S0029-7844(00)01228-X 10.1089/acm.2008.0406 10.1213/01.ANE.0000055818.64084.41 10.12968/bjcn.2004.9.9.15936 10.1046/j.1365-2044.1998.00369.x 10.1111/j.1365-2354.2004.00446.x 10.1089/acm.2007.0817 10.1111/j.1048-891X.2004.14603.x 10.1007/s00520-008-0528-8 10.1016/j.ctcp.2010.05.001 |
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Copyright | Copyright Iranian Hospital Dubai Feb 2013 Copyright © 2013, Iranian Red Crescent Medical Journal; Published by Kowsar Corp. 2013 |
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Snippet | Background : Chemotherapy-induced nausea and vomiting are the most important complications for cancer patients as its prevalence has been reported to be about... Chemotherapy-induced nausea and vomiting are the most important complications for cancer patients as its prevalence has been reported to be about 54-96... BACKGROUNDChemotherapy-induced nausea and vomiting are the most important complications for cancer patients as its prevalence has been reported to be about... |
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SubjectTerms | Cancer Chemotherapy Herbs Patients Therapeutic use Treatment الأدوية السرطان العلاج الكيميائي المرضى |
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Title | Effect of herbal therapy to intensity chemotherapy-induced nausea and vomiting in cancer patients |
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