Accelerated reactions of amines with carbon dioxide driven by superacid at the microdroplet interface

• Published in: Chemical science (Cambridge) Vol. 12; no. 6; pp. 2242 - 225
• Main Authors: Huang, Kai-Hung, Wei, Zhenwei, Cooks, R. Graham
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 21.12.2020; The Royal Society of Chemistry
• Subjects: Amines; Carbon dioxide; Carboxylic acids; Chemistry; Diamines; Imidazole; Ionization; Ions; Mass spectrometry; Protonation; Reaction products; Reagents

Microdroplets display distinctive interfacial chemistry, manifested as accelerated reactions relative to those observed for the same reagents in bulk. Carbon dioxide undergoes C-N bond formation reactions with amines at the interface of droplets to form carbamic acids. Electrospray ionization mass s...