Determination of binding characteristics as a measure for effective albumin using different methods

• Published in: Biochimica et biophysica acta. General subjects Vol. 1867; no. 9; p. 130427
• Main Authors: Paar, Margret, Fengler, Vera H., Reibnegger, Gilbert, Schnurr, Kerstin, Waterstradt, Katja, Schwaminger, Sebastian P., Stauber, Rudolf E., Oettl, Karl
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2023
• Subjects: Acute decompensation; Binding properties; Chronic liver failure; Dansylsarcosine; Effective albumin; electron paramagnetic resonance; Human serum albumin; Oxidative modification; ACLF; Binding properties; BE; EPR; PTM; Oxidative modification; DS; Effective albumin; w/o; NEFA; HSA; Acute decompensation; KB C; Cys; HMA; FA/alb; Dansylsarcosine; Human serum albumin; AD; A.U; electron paramagnetic resonance; DTE; Chronic liver failure; Kd; HNA; FA; HC

Transport functions of albumin are of clinical and pharmacological interest and are determined by albumin's properties like posttranslational modifications or bound ligands. Both are affected in pathological conditions and in therapeutic grade albumin solutions. The term effective albumin conce...