A pH reversibly activatable NIR photothermal/photodynamic-in-one agent integrated with renewable nanoimplants for image-guided precision phototherapy

• Published in: Chemical science (Cambridge) Vol. 12; no. 1; pp. 442 - 452
• Main Authors: Zhao, Xu, Zhao, Kai-Chao, Chen, Li-Jian, Liu, Yu-Shi, Liu, Jia-Lin, Yan, Xiu-Ping
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 31.10.2020; Royal Society of Chemistry; The Royal Society of Chemistry
• Subjects: Anticancer properties; Biotin; Blood circulation; Bromination; Chemical compounds; Chemistry; Chemistry, Multidisciplinary; Image enhancement; Infrared imagery; Light therapy; Mass spectra; Nanoparticles; Near infrared radiation; NMR; Nuclear magnetic resonance; Pharmacology; Physical Sciences; Polyethylene glycol; Radiation damage; Science & Technology; Tumors; PHOTODYNAMIC THERAPY; INDOCYANINE GREEN; PERSISTENT LUMINESCENCE NANOPARTICLES

Phototherapy has great potential to revolutionize conventional therapeutic modalities. However, most phototherapeutic strategies based on multicomponent therapeutic agents generally lack tumor-specificity, resulting in asynchronous therapy and superimposed side-effects. Severe heat damage is also in...