Baicalin and its metabolites suppresses gluconeogenesis through activation of AMPK or AKT in insulin resistant HepG-2 cells - Wang, Tao; Jiang, Hongmei; Cao, Shijie; Chen, Qian; Cui, Mingyuan; Wang, Zhijie; Li, Dandan; Zhou, Jing; Wang, Tao; Qiu, Feng; Kang, Ning (European journal of medicinal chemistry, 2017)
Keywords: AMP-Activated Protein Kinases - metabolism; Antihyperglycemic effect; Baicalin; Cell Survival - drug effects; Dose-Response Relationship, Drug; Flavonoids - chemistry; Flavonoids - metabolism; Flavonoids - pharmacology; Gluconeogenesis - drug effects; Gluconeogenic genes; Hep G2 Cells; Humans; Hypoglycemic Agents - chemistry; Hypoglycemic Agents - metabolism; Hypoglycemic Agents - pharmacology; Insulin Resistance; Insulin-Secreting Cells - drug effects; Metabolites; Molecular Structure; Proto-Oncogene Proteins c-akt - metabolism; Structure-Activity Relationship; Tumor Cells, Cultured; Gluconeogenic genes; Metabolites; Antihyperglycemic effect; Baicalin