Vascular restenosis reduction with platelet membrane coated nanoparticle directed M2 macrophage polarization

• Published in: iScience Vol. 25; no. 10; p. 105147
• Main Authors: Li, Fengshi, Rong, Zhihua, Zhang, Rui, Niu, Shuai, Di, Xiao, Ni, Leng, Liu, Changwei
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 21.10.2022; Elsevier
• Subjects: Drug delivery system; immune response; nanoparticles; immune response; Drug delivery system; nanoparticles

Vascular restenosis is the main factor affecting the prognosis of angioplasty in cardiovascular diseases, and inflammation is a central link in the progression of restenosis. Previous research that applies interleukin 10 (IL10) nanoparticles can effectively regulate local inflammation, but their tar...