Functional assistance for stress distribution in cell culture membrane under periodically stretching

• Published in: Journal of biomechanics Vol. 125; p. 110564
• Main Authors: Dai, Zhi-Xuan, Shih, Po-Jen, Yen, Jia-Yush, Wang, I-Jong
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 26.08.2021; Elsevier Limited
• Subjects: Cell adhesion; Cell culture; Cell proliferation; Cornea; Cyclic stretching; Experiments; Fibroblasts; Finite element analysis; Finite element analysis (FEA); Human keratinocytes; Keratinocytes; Shear strain; Shear stress; Smooth muscle; Stem cells; Stress concentration; Stress distribution; Stretching; United States > US; Taiwan; Stress distribution; Human keratinocytes; Cyclic stretching; Finite element analysis (FEA)

Dynamic cell cultures simulate the in vivo cell environment for a regular loading system with curtain strains. However, it is difficult to obtain strains that are suitable for cells without conducting multiple trials. This study develops a device that increases the strain gradient by changing the te...