Clinical significance of C-reactive protein/platelet ratio from diagnosis to allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia

• Published in: Annals of hematology Vol. 104; no. 7; pp. 3733 - 3743
• Main Authors: Izumi, Akihiko, Tachibana, Takayoshi, Nukui, Jun, Miyazaki, Takuya, Hirose, Natsuki, Ohashi, Takuma, Tanaka, Marika, Katsuki, Kengo, Suzuki, Taisei, Nakajima, Yuki, Matsumoto, Kenji, Fujisawa, Shin, Tanaka, Masatsugu, Nakajima, Hideaki
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2025; Springer Nature B.V
• Subjects: Adolescent; Adult; Aged; Allografts; Blood platelets; Blood Platelets - metabolism; Bone marrow; C-reactive protein; C-Reactive Protein - analysis; C-Reactive Protein - metabolism; Clinical Relevance; Female; Graft versus host disease; Hematology; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Leukemia, Myeloid, Acute - blood; Leukemia, Myeloid, Acute - diagnosis; Leukemia, Myeloid, Acute - mortality; Leukemia, Myeloid, Acute - therapy; Male; Medicine; Medicine & Public Health; Middle Aged; Mortality; Oncology; Patients; Platelet Count; Remission (Medicine); Retrospective Studies; Stem cell transplantation; Survival Rate; Transplantation, Homologous; Young Adult; Biomarkers; CRP to platelet ratio; Acute myeloid leukemia; Allogeneic hematopoietic cell transplantation

Previous studies have shown that C-reactive protein/platelet ratio (CPR) before allogeneic hematopoietic stem cell transplantation (HSCT) is a predictor of survival in patients with hematological malignancies. This multicenter retrospective study aimed to evaluate the clinical significance of CPR fr...