A causal role for the anterior mid-cingulate cortex in negative affect and cognitive control

• Published in: Brain (London, England : 1878) Vol. 139; no. 6; pp. 1844 - 1854
• Main Authors: Tolomeo, Serenella, Christmas, David, Jentzsch, Ines, Johnston, Blair, Sprengelmeyer, Reiner, Matthews, Keith, Douglas Steele, J.
• Format: Journal Article
• Language: English
• Published: England 01.06.2016
• Subjects: Affect - physiology; Case-Control Studies; Cognition - physiology; Depressive Disorder, Treatment-Resistant - diagnostic imaging; Depressive Disorder, Treatment-Resistant - pathology; Depressive Disorder, Treatment-Resistant - physiopathology; Depressive Disorder, Treatment-Resistant - surgery; Facial Expression; Female; Gyrus Cinguli - pathology; Gyrus Cinguli - physiopathology; Gyrus Cinguli - surgery; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Stroop Test; cingulotomy; treatment-resistant depression; cognitive control; mid-cingulate cortex

Converging evidence has linked the anterior mid-cingulate cortex to negative affect, pain and cognitive control. It has previously been proposed that this region uses information about punishment to control aversively motivated actions. Studies on the effects of lesions allow causal inferences about...