Carvedilol to reduce the risk of decompensation in patients with compensated cirrhosis: Is it really needed in patients with cured HCV or suppressed HBV?
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| Published in | Journal of hepatology Vol. 79; no. 5; pp. e200 - e202 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Elsevier B.V
01.11.2023
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| Online Access | Get full text |
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| Author | Primignani, Massimo Degasperi, Elisabetta Lampertico, Pietro Tosetti, Giulia Farina, Elisa |
|---|---|
| Author_xml | – sequence: 1 givenname: Giulia surname: Tosetti fullname: Tosetti, Giulia organization: Division of Gastroenterology and Hepatology, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy – sequence: 2 givenname: Elisabetta surname: Degasperi fullname: Degasperi, Elisabetta organization: Division of Gastroenterology and Hepatology, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy – sequence: 3 givenname: Elisa surname: Farina fullname: Farina, Elisa organization: Division of Gastroenterology and Hepatology, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy – sequence: 4 givenname: Massimo orcidid: 0000-0003-1588-2643 surname: Primignani fullname: Primignani, Massimo email: massimo.primignani@policlinico.mi.it organization: Division of Gastroenterology and Hepatology, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy – sequence: 5 givenname: Pietro surname: Lampertico fullname: Lampertico, Pietro organization: Division of Gastroenterology and Hepatology, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy |
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| Cites_doi | 10.1002/hep.23045 10.1016/j.jhep.2022.05.021 10.1016/j.jhep.2013.11.019 10.1136/gutjnl-2016-311735 10.14309/ajg.0000000000001158 10.1016/S0140-6736(18)31875-0 10.1053/j.gastro.2016.09.009 |
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| Copyright | 2023 European Association for the Study of the Liver |
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| References | Tripathi, Ferguson, Kochar, Leithead, Therapondos, McAvoy (bib2) 2009; 50 Shah, Azam, Rauf, Abid, Hamid, Jafri (bib3) 2014; 60 Villanueva, Albillos, Genescà, Garcia-Pagan, Calleja, Aracil (bib5) 2019; 393 Bhardwaj, Kedarisetty, Vashishtha, Bhadoria, Jindal, Kumar (bib4) 2017; 66 Tosetti, Degasperi, Farina, D’Ambrosio, Soffredini, Borghi (bib6) 2021; 116 Villanueva, Torres, Sarin, Shah, Tripathi, Brujats (bib1) 2022 Oct; 77 Nahon, Bourcier, Layese, Audureau, Cagnot, Marcellin (bib7) 2017; 152 Bhardwaj (10.1016/j.jhep.2023.03.026_bib4) 2017; 66 Nahon (10.1016/j.jhep.2023.03.026_bib7) 2017; 152 Villanueva (10.1016/j.jhep.2023.03.026_bib1) 2022; 77 Shah (10.1016/j.jhep.2023.03.026_bib3) 2014; 60 Tripathi (10.1016/j.jhep.2023.03.026_bib2) 2009; 50 Villanueva (10.1016/j.jhep.2023.03.026_bib5) 2019; 393 Tosetti (10.1016/j.jhep.2023.03.026_bib6) 2021; 116 |
| References_xml | – volume: 152 start-page: 142 year: 2017 end-page: 156 ident: bib7 article-title: Eradication of Hepatitis C Virus infection in patients with cirrhosis reduces risk of liver and non-liver complications publication-title: Gastroenterology – volume: 77 start-page: 1014 year: 2022 Oct end-page: 1025 ident: bib1 article-title: Carvedilol-IPD-MA-group and the Baveno Cooperation: an EASL Consortium. Carvedilol reduces the risk of decompensation and mortality in patients with compensated cirrhosis in a competing-risk meta-analysis publication-title: J Hepatol – volume: 50 start-page: 825 year: 2009 end-page: 833 ident: bib2 article-title: Randomized controlled trial of carvedilol versus variceal band ligation for the prevention of the first variceal bleed publication-title: Hepatology – volume: 60 start-page: 757 year: 2014 end-page: 764 ident: bib3 article-title: Carvedilol vs. esophageal variceal band ligation in the primary prophylaxis of variceal hemorrhage: a multicentre randomized controlled trial publication-title: J Hepatol – volume: 116 start-page: 1342 year: 2021 end-page: 1344 ident: bib6 article-title: Decompensation in Direct-Acting Antiviral cured Hepatitis C Virus compensated patients with clinically significant portal hypertension: too Rare to warrant universal B-Blocker Therapy publication-title: Am J Gastroenterol – volume: 66 start-page: 1838 year: 2017 end-page: 1894 ident: bib4 article-title: Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial publication-title: Gut – volume: 393 start-page: 1597 year: 2019 end-page: 1608 ident: bib5 article-title: β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial publication-title: Lancet – volume: 50 start-page: 825 issue: 3 year: 2009 ident: 10.1016/j.jhep.2023.03.026_bib2 article-title: Randomized controlled trial of carvedilol versus variceal band ligation for the prevention of the first variceal bleed publication-title: Hepatology doi: 10.1002/hep.23045 – volume: 77 start-page: 1014 issue: 4 year: 2022 ident: 10.1016/j.jhep.2023.03.026_bib1 article-title: Carvedilol-IPD-MA-group and the Baveno Cooperation: an EASL Consortium. Carvedilol reduces the risk of decompensation and mortality in patients with compensated cirrhosis in a competing-risk meta-analysis publication-title: J Hepatol doi: 10.1016/j.jhep.2022.05.021 – volume: 60 start-page: 757 issue: 4 year: 2014 ident: 10.1016/j.jhep.2023.03.026_bib3 article-title: Carvedilol vs. esophageal variceal band ligation in the primary prophylaxis of variceal hemorrhage: a multicentre randomized controlled trial publication-title: J Hepatol doi: 10.1016/j.jhep.2013.11.019 – volume: 66 start-page: 1838 issue: 10 year: 2017 ident: 10.1016/j.jhep.2023.03.026_bib4 article-title: Carvedilol delays the progression of small oesophageal varices in patients with cirrhosis: a randomised placebo-controlled trial publication-title: Gut doi: 10.1136/gutjnl-2016-311735 – volume: 116 start-page: 1342 issue: 6 year: 2021 ident: 10.1016/j.jhep.2023.03.026_bib6 article-title: Decompensation in Direct-Acting Antiviral cured Hepatitis C Virus compensated patients with clinically significant portal hypertension: too Rare to warrant universal B-Blocker Therapy publication-title: Am J Gastroenterol doi: 10.14309/ajg.0000000000001158 – volume: 393 start-page: 1597 issue: 10181 year: 2019 ident: 10.1016/j.jhep.2023.03.026_bib5 article-title: β blockers to prevent decompensation of cirrhosis in patients with clinically significant portal hypertension (PREDESCI): a randomised, double-blind, placebo-controlled, multicentre trial publication-title: Lancet doi: 10.1016/S0140-6736(18)31875-0 – volume: 152 start-page: 142 year: 2017 ident: 10.1016/j.jhep.2023.03.026_bib7 article-title: Eradication of Hepatitis C Virus infection in patients with cirrhosis reduces risk of liver and non-liver complications publication-title: Gastroenterology doi: 10.1053/j.gastro.2016.09.009 |
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