Tiotropium Respimat Efficacy and Safety in Asthma: Relationship to Age

• Published in: The journal of allergy and clinical immunology in practice (Cambridge, MA) Vol. 8; no. 8; p. 2653
• Main Authors: Doherty, Dennis E, Bleecker, Eugene R, Moroni-Zentgraf, Petra, Zaremba-Pechmann, Liliana, Kerstjens, Huib A M
• Format: Journal Article
• Language: English
• Published: United States 01.09.2020
• Subjects: Administration, Inhalation; Adult; Aged; Asthma - drug therapy; Bronchodilator Agents - therapeutic use; Double-Blind Method; Humans; Middle Aged; Salmeterol Xinafoate - therapeutic use; Tiotropium Bromide - therapeutic use; Treatment Outcome; Aging; Pharmacotherapy; Long-acting β-agonists; Long-acting muscarinic antagonist; Asthma

Data are limited on the differential response to long-acting bronchodilators in older versus younger adults with asthma. To determine whether the response to tiotropium Respimat differed in older versus younger patients with asthma. Post hoc analyses of 4 randomized, double-blind, placebo-controlled...