The protective effect of coffee consumption on cutaneous melanoma risk and the role of GSTM1 and GSTT1 polymorphisms

• Published in: Cancer causes & control Vol. 24; no. 10; pp. 1779 - 1787
• Main Authors: Fortes, Cristina, Mastroeni, Simona, Boffetta, Paolo, Antonelli, Gianluca, Pilla, Maria Antonietta, Bottà, Giordano, Anzidei, Patrizia, Venanzetti, Federica
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer 01.10.2013; Springer Netherlands; Springer Nature B.V; Springer Verlag
• Subjects: Adult; Aged; Aged, 80 and over; Alcohol drinking; Biomedical and Life Sciences; Biomedicine; Body mass index; Cancer Research; Case-Control Studies; Cigarette smoking; Coffee; Epidemiology; Genetic Predisposition to Disease; Genotype; Genotypes; Glutathione Transferase - genetics; Glutathione Transferase - metabolism; Hair; Hematology; Hospitals; Humans; Italy - epidemiology; Life Sciences; Melanoma; Melanoma - enzymology; Melanoma - epidemiology; Melanoma - genetics; Melanoma - prevention & control; Melanoma, Cutaneous Malignant; Middle Aged; Nevus; Oncology; Original Paper; Phytochemicals; Polymorphism, Genetic; Protective effects; Public Health; Questionnaires; Random Allocation; Risk Assessment; Santé publique et épidémiologie; Skin; Skin cancer; Skin diseases; Skin Neoplasms; Sociodemographics; Sunburn & sun tanning; White people; Young Adult; Rome Italy; Italy; GSTT1; GSTM1; Diet; Coffee; Polymorphisms; Melanoma

Purposes: The authors examined the association between coffee consumption and cutaneous melanoma and the implication of GSTM1 and GSTT1 polymorphisms. Methods: A hospital-based case-control study was conducted in the inpatient wards of IDI-San Carlo Rome, Italy, including 304 incident cases of cutan...