The effects of the activation of the inner-hair-cell basolateral K+ channels on auditory nerve responses

• Published in: Hearing research Vol. 364; pp. 68 - 80
• Main Authors: Altoè, Alessandro, Pulkki, Ville, Verhulst, Sarah
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.07.2018
• Subjects: Adaptation; Auditory nerve; Inner hair cell; K+ channels; Phase-locking; Recovery; Inner hair cell; K+ channels; Phase-locking; Auditory nerve; Recovery; Adaptation; K(+) channels

The basolateral membrane of the mammalian inner hair cell (IHC) expresses large voltage and Ca2+ gated outward K+ currents. To quantify how the voltage-dependent activation of the K+ channels affects the functionality of the auditory nerve innervating the IHC, this study adopts a model of mechanical...