Takotsubo syndrome: State-of-the-art review by an expert panel – Part 1
Takotsubo syndrome (TTS) is an acute cardiac condition independent of epicardial coronary obstruction that mimics acute coronary syndrome and is characterized by acute heart failure with reversible ventricular motion abnormalities. This consensus paper is the result of a multinational effort aiming...
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| Published in | Cardiovascular revascularization medicine Vol. 20; no. 1; pp. 70 - 79 |
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| Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.01.2019
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| Online Access | Get full text |
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| Abstract | Takotsubo syndrome (TTS) is an acute cardiac condition independent of epicardial coronary obstruction that mimics acute coronary syndrome and is characterized by acute heart failure with reversible ventricular motion abnormalities. This consensus paper is the result of a multinational effort aiming to summarize the current state of the art on TTS. Experts in the field provide a thorough and detailed review of this syndrome. Several novel and unique sections are emphasized in this document, including the current state of the art on genetics of takotsubo syndrome, microRNAs (miRs), racial differences, role of cardiac spectroscopy and intracoronary imaging, as well as mechanical circulatory support.
In part 1 of this two-part manuscript, we discuss how TTS came to be known, several patterns and forms it can take in patients, epidemiology and pathophysiology of the syndrome, and clinical presentation.
•Takotsubo syndrome was first described in 1986.•TTS mimics ACS and is characterized by acute heart failure.•International experts provide a thorough review of TTS. |
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| AbstractList | Takotsubo syndrome (TTS) is an acute cardiac condition independent of epicardial coronary obstruction that mimics acute coronary syndrome and is characterized by acute heart failure with reversible ventricular motion abnormalities. This consensus paper is the result of a multinational effort aiming to summarize the current state of the art on TTS. Experts in the field provide a thorough and detailed review of this syndrome. Several novel and unique sections are emphasized in this document, including the current state of the art on genetics of takotsubo syndrome, microRNAs (miRs), racial differences, role of cardiac spectroscopy and intracoronary imaging, as well as mechanical circulatory support.
In part 1 of this two-part manuscript, we discuss how TTS came to be known, several patterns and forms it can take in patients, epidemiology and pathophysiology of the syndrome, and clinical presentation.
•Takotsubo syndrome was first described in 1986.•TTS mimics ACS and is characterized by acute heart failure.•International experts provide a thorough review of TTS. Takotsubo syndrome (TTS) is an acute cardiac condition independent of epicardial coronary obstruction that mimics acute coronary syndrome and is characterized by acute heart failure with reversible ventricular motion abnormalities. This consensus paper is the result of a multinational effort aiming to summarize the current state of the art on TTS. Experts in the field provide a thorough and detailed review of this syndrome. Several novel and unique sections are emphasized in this document, including the current state of the art on genetics of takotsubo syndrome, microRNAs (miRs), racial differences, role of cardiac spectroscopy and intracoronary imaging, as well as mechanical circulatory support. In part 1 of this two-part manuscript, we discuss how TTS came to be known, several patterns and forms it can take in patients, epidemiology and pathophysiology of the syndrome, and clinical presentation. |
| Author | Eitel, Ingo Santoro, Francesco Salmoirago-Blotcher, Elena Akasaka, Takashi Hebert, Kathy Sharkey, Scott W. Kajita, Alexandre H. Ben-Dor, Itsik Brunetti, Natale Daniele Dias, Andre Madias, John E. Núñez Gil, Ivan J. Akashi, Yoshihiro J. Dawson, Dana Ozaki, Yuichi Jaguszewski, Milosz Napp, L. Christian Kurisu, Satoshi Figueredo, Vincent M. Christensen, Thomas Emil Pelliccia, Francesco Lerman, Amir Franco, Emiliana García-Garcia, Héctor M. Waksman, Ron El-Battrawy, Ibrahim Akin, Ibrahim |
| Author_xml | – sequence: 1 givenname: Andre surname: Dias fullname: Dias, Andre organization: Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States of America – sequence: 2 givenname: Ivan J. surname: Núñez Gil fullname: Núñez Gil, Ivan J. organization: Interventional Cardiology, Cardiovascular Institute, Hospital Clínico San Carlos, Madrid, Spain – sequence: 3 givenname: Francesco surname: Santoro fullname: Santoro, Francesco organization: Department of Medical & Surgery Sciences, University of Foggia, Foggia, Italy – sequence: 4 givenname: John E. surname: Madias fullname: Madias, John E. organization: Icahn School of Medicine at Mount Sinai/Division of Cardiology, Elmhurst Hospital Center, Elmhurst, NY, United States of America – sequence: 5 givenname: Francesco surname: Pelliccia fullname: Pelliccia, Francesco organization: Interventional Cardiology Unit, Sapienza University, Rome, Italy – sequence: 6 givenname: Natale Daniele surname: Brunetti fullname: Brunetti, Natale Daniele organization: Department of Medical & Surgery Sciences, University of Foggia, Foggia, Italy – sequence: 7 givenname: Elena surname: Salmoirago-Blotcher fullname: Salmoirago-Blotcher, Elena organization: Centers for Behavioral and Preventive Medicine, The Miriam Hospital, Warren Alpert Medical School of Brown University, Providence, RI, United States of America – sequence: 8 givenname: Scott W. surname: Sharkey fullname: Sharkey, Scott W. organization: Minneapolis Heart Institute Foundation, Minneapolis, MN, United States of America – sequence: 9 givenname: Ingo surname: Eitel fullname: Eitel, Ingo organization: Cardiology, Angiology, Intensive Care Medicine, University Lübeck, Schleswig-Holstein, Germany – sequence: 10 givenname: Yoshihiro J. surname: Akashi fullname: Akashi, Yoshihiro J. organization: Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan – sequence: 11 givenname: Ibrahim surname: El-Battrawy fullname: El-Battrawy, Ibrahim organization: Department of Internal Medicine, University Heidelberg, Mannheim, Germany – sequence: 12 givenname: Emiliana surname: Franco fullname: Franco, Emiliana organization: Department of Cardiology, Einstein Medical Center, Philadelphia, PA, United States of America – sequence: 13 givenname: Ibrahim surname: Akin fullname: Akin, Ibrahim organization: Department of Internal Medicine, University Heidelberg, Mannheim, Germany – sequence: 14 givenname: Milosz surname: Jaguszewski fullname: Jaguszewski, Milosz organization: Department of Cardiology, Medical University of Gdansk, Poland – sequence: 15 givenname: Dana surname: Dawson fullname: Dawson, Dana organization: School of Medicine and Dentistry, University of Aberdeen, Aberdeen, UK – sequence: 16 givenname: Vincent M. surname: Figueredo fullname: Figueredo, Vincent M. organization: Department of Cardiology, Einstein Medical Center, Philadelphia, PA, United States of America – sequence: 17 givenname: L. Christian surname: Napp fullname: Napp, L. Christian organization: Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany – sequence: 18 givenname: Thomas Emil surname: Christensen fullname: Christensen, Thomas Emil organization: Copenhagen University Hospital, Copenhagen, Denmark – sequence: 19 givenname: Kathy surname: Hebert fullname: Hebert, Kathy organization: GE Healthcare, Miami, FL, United States of America – sequence: 20 givenname: Itsik surname: Ben-Dor fullname: Ben-Dor, Itsik organization: Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States of America – sequence: 21 givenname: Yuichi surname: Ozaki fullname: Ozaki, Yuichi organization: Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States of America – sequence: 22 givenname: Héctor M. surname: García-Garcia fullname: García-Garcia, Héctor M. organization: Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States of America – sequence: 23 givenname: Alexandre H. surname: Kajita fullname: Kajita, Alexandre H. organization: Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States of America – sequence: 24 givenname: Takashi surname: Akasaka fullname: Akasaka, Takashi organization: Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan – sequence: 25 givenname: Satoshi surname: Kurisu fullname: Kurisu, Satoshi organization: Department of Cardiovascular Medicine, Hiroshima University, Hiroshima, Japan – sequence: 26 givenname: Amir surname: Lerman fullname: Lerman, Amir organization: Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States of America – sequence: 27 givenname: Ron surname: Waksman fullname: Waksman, Ron email: ron.waksman@medstar.net organization: Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, United States of America |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30528096$$D View this record in MEDLINE/PubMed |
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| Keywords | CRP Heart failure RV BNP LV Catecholamine miRs ACS Takotsubo TTS MACE TIMI STEMI |
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| Title | Takotsubo syndrome: State-of-the-art review by an expert panel – Part 1 |
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