A bioinspired flexible organic artificial afferent nerve
Sensory (or afferent) nerves bring sensations of touch, pain, or temperature variation to the central nervous system and brain. Using the tools and materials of organic electronics, Kim et al. combined a pressure sensor, a ring oscillator, and an ion gel–gated transistor to form an artificial mechan...
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Published in | Science (American Association for the Advancement of Science) Vol. 360; no. 6392; pp. 998 - 1003 |
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Main Authors | , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
The American Association for the Advancement of Science
01.06.2018
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Subjects | |
Online Access | Get full text |
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Abstract | Sensory (or afferent) nerves bring sensations of touch, pain, or temperature variation to the central nervous system and brain. Using the tools and materials of organic electronics, Kim
et al.
combined a pressure sensor, a ring oscillator, and an ion gel–gated transistor to form an artificial mechanoreceptor (see the Perspective by Bartolozzi). The combination allows for the sensing of multiple pressure inputs, which can be converted into a sensor signal and used to drive the motion of a cockroach leg in an oscillatory pattern.
Science
, this issue p.
998
; see also p.
966
Organic flexible electronics mimic the functions of a biological afferent nerve and actuate muscles.
The distributed network of receptors, neurons, and synapses in the somatosensory system efficiently processes complex tactile information. We used flexible organic electronics to mimic the functions of a sensory nerve. Our artificial afferent nerve collects pressure information (1 to 80 kilopascals) from clusters of pressure sensors, converts the pressure information into action potentials (0 to 100 hertz) by using ring oscillators, and integrates the action potentials from multiple ring oscillators with a synaptic transistor. Biomimetic hierarchical structures can detect movement of an object, combine simultaneous pressure inputs, and distinguish braille characters. Furthermore, we connected our artificial afferent nerve to motor nerves to construct a hybrid bioelectronic reflex arc to actuate muscles. Our system has potential applications in neurorobotics and neuroprosthetics. |
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AbstractList | I've got a feelingSensory (or afferent) nerves bring sensations of touch, pain, or temperature variation to the central nervous system and brain. Using the tools and materials of organic electronics, Kim et al. combined a pressure sensor, a ring oscillator, and an ion gel–gated transistor to form an artificial mechanoreceptor (see the Perspective by Bartolozzi). The combination allows for the sensing of multiple pressure inputs, which can be converted into a sensor signal and used to drive the motion of a cockroach leg in an oscillatory pattern.Science, this issue p. 998; see also p. 966The distributed network of receptors, neurons, and synapses in the somatosensory system efficiently processes complex tactile information. We used flexible organic electronics to mimic the functions of a sensory nerve. Our artificial afferent nerve collects pressure information (1 to 80 kilopascals) from clusters of pressure sensors, converts the pressure information into action potentials (0 to 100 hertz) by using ring oscillators, and integrates the action potentials from multiple ring oscillators with a synaptic transistor. Biomimetic hierarchical structures can detect movement of an object, combine simultaneous pressure inputs, and distinguish braille characters. Furthermore, we connected our artificial afferent nerve to motor nerves to construct a hybrid bioelectronic reflex arc to actuate muscles. Our system has potential applications in neurorobotics and neuroprosthetics. Sensory (or afferent) nerves bring sensations of touch, pain, or temperature variation to the central nervous system and brain. Using the tools and materials of organic electronics, Kim et al. combined a pressure sensor, a ring oscillator, and an ion gel–gated transistor to form an artificial mechanoreceptor (see the Perspective by Bartolozzi). The combination allows for the sensing of multiple pressure inputs, which can be converted into a sensor signal and used to drive the motion of a cockroach leg in an oscillatory pattern. Science , this issue p. 998 ; see also p. 966 Organic flexible electronics mimic the functions of a biological afferent nerve and actuate muscles. The distributed network of receptors, neurons, and synapses in the somatosensory system efficiently processes complex tactile information. We used flexible organic electronics to mimic the functions of a sensory nerve. Our artificial afferent nerve collects pressure information (1 to 80 kilopascals) from clusters of pressure sensors, converts the pressure information into action potentials (0 to 100 hertz) by using ring oscillators, and integrates the action potentials from multiple ring oscillators with a synaptic transistor. Biomimetic hierarchical structures can detect movement of an object, combine simultaneous pressure inputs, and distinguish braille characters. Furthermore, we connected our artificial afferent nerve to motor nerves to construct a hybrid bioelectronic reflex arc to actuate muscles. Our system has potential applications in neurorobotics and neuroprosthetics. The distributed network of receptors, neurons, and synapses in the somatosensory system efficiently processes complex tactile information. We used flexible organic electronics to mimic the functions of a sensory nerve. Our artificial afferent nerve collects pressure information (1 to 80 kilopascals) from clusters of pressure sensors, converts the pressure information into action potentials (0 to 100 hertz) by using ring oscillators, and integrates the action potentials from multiple ring oscillators with a synaptic transistor. Biomimetic hierarchical structures can detect movement of an object, combine simultaneous pressure inputs, and distinguish braille characters. Furthermore, we connected our artificial afferent nerve to motor nerves to construct a hybrid bioelectronic reflex arc to actuate muscles. Our system has potential applications in neurorobotics and neuroprosthetics.The distributed network of receptors, neurons, and synapses in the somatosensory system efficiently processes complex tactile information. We used flexible organic electronics to mimic the functions of a sensory nerve. Our artificial afferent nerve collects pressure information (1 to 80 kilopascals) from clusters of pressure sensors, converts the pressure information into action potentials (0 to 100 hertz) by using ring oscillators, and integrates the action potentials from multiple ring oscillators with a synaptic transistor. Biomimetic hierarchical structures can detect movement of an object, combine simultaneous pressure inputs, and distinguish braille characters. Furthermore, we connected our artificial afferent nerve to motor nerves to construct a hybrid bioelectronic reflex arc to actuate muscles. Our system has potential applications in neurorobotics and neuroprosthetics. The distributed network of receptors, neurons, and synapses in the somatosensory system efficiently processes complex tactile information. We used flexible organic electronics to mimic the functions of a sensory nerve. Our artificial afferent nerve collects pressure information (1 to 80 kilopascals) from clusters of pressure sensors, converts the pressure information into action potentials (0 to 100 hertz) by using ring oscillators, and integrates the action potentials from multiple ring oscillators with a synaptic transistor. Biomimetic hierarchical structures can detect movement of an object, combine simultaneous pressure inputs, and distinguish braille characters. Furthermore, we connected our artificial afferent nerve to motor nerves to construct a hybrid bioelectronic reflex arc to actuate muscles. Our system has potential applications in neurorobotics and neuroprosthetics. |
Author | Niu, Simiao Kim, Yeongin Liu, Yuxin Kang, Jiheong Zhu, Chenxin Bao, Zhenan Oh, Jin Young Foudeh, Amir M. Xu, Wentao Lee, Yeongjun Lee, Tae-Woo Son, Donghee Liu, Jia Chortos, Alex Pfattner, Raphael |
Author_xml | – sequence: 1 givenname: Yeongin orcidid: 0000-0002-9495-3165 surname: Kim fullname: Kim, Yeongin organization: Department of Electrical Engineering, Stanford University, Stanford, CA, USA – sequence: 2 givenname: Alex surname: Chortos fullname: Chortos, Alex organization: Department of Materials Science and Engineering, Stanford University, Stanford, CA, USA – sequence: 3 givenname: Wentao orcidid: 0000-0002-1054-6037 surname: Xu fullname: Xu, Wentao organization: Department of Materials Science and Engineering, Seoul National University, Seoul, South Korea., Institute of Photoelectronic Thin Film Devices and Technology, Nankai University, Tianjin, China – sequence: 4 givenname: Yuxin surname: Liu fullname: Liu, Yuxin organization: Department of Bioengineering, Stanford University, Stanford, CA, USA – sequence: 5 givenname: Jin Young orcidid: 0000-0003-2260-9960 surname: Oh fullname: Oh, Jin Young organization: Department of Chemical Engineering, Stanford University, Stanford, CA, USA., Department of Chemical Engineering, Kyung Hee University, Yongin, South Korea – sequence: 6 givenname: Donghee surname: Son fullname: Son, Donghee organization: Department of Chemical Engineering, Stanford University, Stanford, CA, USA – sequence: 7 givenname: Jiheong surname: Kang fullname: Kang, Jiheong organization: Department of Chemical Engineering, Stanford University, Stanford, CA, USA – sequence: 8 givenname: Amir M. surname: Foudeh fullname: Foudeh, Amir M. organization: Department of Chemical Engineering, Stanford University, Stanford, CA, USA – sequence: 9 givenname: Chenxin surname: Zhu fullname: Zhu, Chenxin organization: Department of Electrical Engineering, Stanford University, Stanford, CA, USA – sequence: 10 givenname: Yeongjun orcidid: 0000-0002-2488-9903 surname: Lee fullname: Lee, Yeongjun organization: Department of Materials Science and Engineering, Seoul National University, Seoul, South Korea – sequence: 11 givenname: Simiao surname: Niu fullname: Niu, Simiao organization: Department of Chemical Engineering, Stanford University, Stanford, CA, USA – sequence: 12 givenname: Jia orcidid: 0000-0003-2217-6982 surname: Liu fullname: Liu, Jia organization: Department of Chemical Engineering, Stanford University, Stanford, CA, USA – sequence: 13 givenname: Raphael orcidid: 0000-0002-7232-1845 surname: Pfattner fullname: Pfattner, Raphael organization: Department of Chemical Engineering, Stanford University, Stanford, CA, USA – sequence: 14 givenname: Zhenan orcidid: 0000-0002-0972-1715 surname: Bao fullname: Bao, Zhenan organization: Department of Chemical Engineering, Stanford University, Stanford, CA, USA – sequence: 15 givenname: Tae-Woo orcidid: 0000-0002-6449-6725 surname: Lee fullname: Lee, Tae-Woo organization: Department of Materials Science and Engineering, Seoul National University, Seoul, South Korea |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29853682$$D View this record in MEDLINE/PubMed |
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Snippet | Sensory (or afferent) nerves bring sensations of touch, pain, or temperature variation to the central nervous system and brain. Using the tools and materials... The distributed network of receptors, neurons, and synapses in the somatosensory system efficiently processes complex tactile information. We used flexible... I've got a feelingSensory (or afferent) nerves bring sensations of touch, pain, or temperature variation to the central nervous system and brain. Using the... |
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SubjectTerms | Afferent Pathways Anatomy Bioelectricity Biomimetic Materials Biomimetics Braille Brain Central nervous system Computer networks Electronics Information processing Mechanoreceptors Motor Neurons Muscle Contraction Muscles Muscles - innervation Muscles - physiology Nerves Neural Prostheses Oscillators Pain Pressure Pressure sensors Prosthetics Receptors Robotics Sensory neurons Somatosensory system Structural hierarchy Synapses Transistors |
Title | A bioinspired flexible organic artificial afferent nerve |
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