Contrast medium volume to creatinine clearance ratio: A predictor of contrast-induced nephropathy in the first 72 hours following percutaneous coronary intervention

• Published in: Catheterization and cardiovascular interventions Vol. 79; no. 1; pp. 70 - 75
• Main Authors: Tan, Ning, Liu, Yong, Zhou, Ying-Ling, He, Peng-Cheng, Yang, Jun-Qing, Luo, Jian-Fang, Chen, Ji-Yan
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.01.2012
• Subjects: Adult; Aged; Angioplasty, Balloon, Coronary; Biomarkers - blood; China; Contrast Media - adverse effects; Contrast Media - pharmacokinetics; contrast medium; contrast-induced nephropathy; Creatinine - blood; creatinine clearance; diabetes; Female; Humans; Kidney Diseases - blood; Kidney Diseases - chemically induced; Kidney Diseases - diagnosis; Kidney Diseases - prevention & control; Logistic Models; Male; Middle Aged; Multivariate Analysis; percutaneous coronary intervention; Predictive Value of Tests; Prospective Studies; Radiography, Interventional - adverse effects; Risk Assessment; Risk Factors; ROC Curve; Sensitivity and Specificity; Time Factors; Treatment Outcome; Up-Regulation; China

Objectives: To investigate the predictive value of the contrast media volume to creatinine clearance (V/CrCl) ratio for the risk of contrast‐induced nephropathy (CIN) (i.e., within 48–72 hr) and to determine a relatively safe V/CrCl cut‐off value to avoid CIN in patients following percutaneous coron...