Persistence with prescribed antimuscarinic therapy for overactive bladder: a UK experience

Study Type – Therapy (prevalence) Level of Evidence 2b What's known on the subject? and What does the study add? Persistence with long‐term medication in chronic diseases is typically low and that for overactive bladder medication is lower than average. Sub‐optimal persistence is a major challe...

Full description

Saved in:
Bibliographic Details
Published inBJU international Vol. 110; no. 11; pp. 1767 - 1774
Main Authors Wagg, Adrian, Compion, Gerhard, Fahey, Amanda, Siddiqui, Emad
Format Journal Article
LanguageEnglish
Published Oxford, UK Blackwell Publishing Ltd 01.12.2012
Wiley-Blackwell
Wiley Subscription Services, Inc
Subjects
Online AccessGet full text
ISSN1464-4096
1464-410X
1464-410X
DOI10.1111/j.1464-410X.2012.11023.x

Cover

Loading…
Abstract Study Type – Therapy (prevalence) Level of Evidence 2b What's known on the subject? and What does the study add? Persistence with long‐term medication in chronic diseases is typically low and that for overactive bladder medication is lower than average. Sub‐optimal persistence is a major challenge for the successful management of overactive bladder. Using UK prescription data, persistence was generally low across the range of antimuscarinics. Patients aged 60 years and above were more likely to persist with prescribed oral antimuscarinic drugs than younger patients (40–59 years). Solifenacin was consistently associated with the highest rate of persistence compared with the other antimuscarinics included in the study OBJECTIVES •  To describe the level of persistence for patients receiving antimuscarinics for overactive bladder (OAB) over a 12‐month period based on real prescription data from the UK. •  To investigate patterns of persistence with oral antimuscarinic drugs prescribed for OAB, across different age groups. PATIENTS AND METHODS •  UK prescription data from a longitudinal patient database were analysed retrospectively to assess persistence with darifenacin, flavoxate, oxybutynin (extended release [ER] and immediate release [IR]), propiverine, solifenacin, tolterodine (ER/IR) and trospium. •  Data were extracted from the medical records of >1 200 000 registered patients via general practice software, and anonymized prescription data were collated for all eligible patients with documented OAB (n= 4833). •  Data were collected on patients who started treatment between January 2007 and December 2007 and were collected up to December 2008, to allow each patient a full 12‐month potential treatment period. Failure of persistence was declared after a gap of at least 1.5 times the length of the period of the most recent prescription. •  The analysis included only patients who were new to a course of treatment (i.e. who had not been prescribed that particular treatment or dosage for at least 6 months before the study period). RESULTS •  The number of patients prescribed each antimuscarinic drug varied from 23 for darifenacin to 1758 for tolterodine ER. •  The longest mean persistence was reported for solifenacin (187 days versus 77−157 days for the other treatments). •  At 3 months, the proportions of patients still on their original treatment were: solifenacin 58%, darifenacin 52%, tolterodine ER 47%, propiverine 47%, tolterodine IR 46%, oxybutynin ER 44%, trospium 42%, oxybutynin IR 40%, flavoxate 28%. •  At 12 months, the proportions of patients still on their original treatment were: solifenacin 35%, tolterodine ER 28%, propiverine 27%, oxybutynin ER 26%, trospium 26%, tolterodine IR 24%, oxybutynin IR 22%, darifenacin 17%, flavoxate 14%. •  In a sub‐analysis stratified by age, patients aged ≥60 years were more likely to persist with prescribed therapy over the 12‐month period than those aged <60 years. CONCLUSIONS •  Twelve months after the initial prescription, persistence rates with pharmacotherapy in the context of OAB are generally low. •  Solifenacin was associated with higher levels of persistence compared with other prescribed antimuscarinic agents. •  Older people are more likely than younger patients to persist with prescribed therapy. Further studies are required to understand this finding and why patients are more likely to persist with one drug rather than another.
AbstractList Study Type--Therapy (prevalence) Level of Evidence 2b. What's known on the subject? and What does the study add? Persistence with long-term medication in chronic diseases is typically low and that for overactive bladder medication is lower than average. Sub-optimal persistence is a major challenge for the successful management of overactive bladder. Using UK prescription data, persistence was generally low across the range of antimuscarinics. Patients aged 60 years and above were more likely to persist with prescribed oral antimuscarinic drugs than younger patients (40-59 years). Solifenacin was consistently associated with the highest rate of persistence compared with the other antimuscarinics included in the study • To describe the level of persistence for patients receiving antimuscarinics for overactive bladder (OAB) over a 12-month period based on real prescription data from the UK. • To investigate patterns of persistence with oral antimuscarinic drugs prescribed for OAB, across different age groups. • UK prescription data from a longitudinal patient database were analysed retrospectively to assess persistence with darifenacin, flavoxate, oxybutynin (extended release [ER] and immediate release [IR]), propiverine, solifenacin, tolterodine (ER/IR) and trospium. • Data were extracted from the medical records of >1,200,000 registered patients via general practice software, and anonymized prescription data were collated for all eligible patients with documented OAB (n = 4833). • Data were collected on patients who started treatment between January 2007 and December 2007 and were collected up to December 2008, to allow each patient a full 12-month potential treatment period. Failure of persistence was declared after a gap of at least 1.5 times the length of the period of the most recent prescription. • The analysis included only patients who were new to a course of treatment (i.e. who had not been prescribed that particular treatment or dosage for at least 6 months before the study period). • The number of patients prescribed each antimuscarinic drug varied from 23 for darifenacin to 1758 for tolterodine ER. • The longest mean persistence was reported for solifenacin (187 days versus 77-157 days for the other treatments). • At 3 months, the proportions of patients still on their original treatment were: solifenacin 58%, darifenacin 52%, tolterodine ER 47%, propiverine 47%, tolterodine IR 46%, oxybutynin ER 44%, trospium 42%, oxybutynin IR 40%, flavoxate 28%. • At 12 months, the proportions of patients still on their original treatment were: solifenacin 35%, tolterodine ER 28%, propiverine 27%, oxybutynin ER 26%, trospium 26%, tolterodine IR 24%, oxybutynin IR 22%, darifenacin 17%, flavoxate 14%. • In a sub-analysis stratified by age, patients aged ≥ 60 years were more likely to persist with prescribed therapy over the 12-month period than those aged <60 years. • Twelve months after the initial prescription, persistence rates with pharmacotherapy in the context of OAB are generally low. • Solifenacin was associated with higher levels of persistence compared with other prescribed antimuscarinic agents. • Older people are more likely than younger patients to persist with prescribed therapy. Further studies are required to understand this finding and why patients are more likely to persist with one drug rather than another.
Study Type--Therapy (prevalence) Level of Evidence 2b. What's known on the subject? and What does the study add? Persistence with long-term medication in chronic diseases is typically low and that for overactive bladder medication is lower than average. Sub-optimal persistence is a major challenge for the successful management of overactive bladder. Using UK prescription data, persistence was generally low across the range of antimuscarinics. Patients aged 60 years and above were more likely to persist with prescribed oral antimuscarinic drugs than younger patients (40-59 years). Solifenacin was consistently associated with the highest rate of persistence compared with the other antimuscarinics included in the studyUNLABELLEDStudy Type--Therapy (prevalence) Level of Evidence 2b. What's known on the subject? and What does the study add? Persistence with long-term medication in chronic diseases is typically low and that for overactive bladder medication is lower than average. Sub-optimal persistence is a major challenge for the successful management of overactive bladder. Using UK prescription data, persistence was generally low across the range of antimuscarinics. Patients aged 60 years and above were more likely to persist with prescribed oral antimuscarinic drugs than younger patients (40-59 years). Solifenacin was consistently associated with the highest rate of persistence compared with the other antimuscarinics included in the study• To describe the level of persistence for patients receiving antimuscarinics for overactive bladder (OAB) over a 12-month period based on real prescription data from the UK. • To investigate patterns of persistence with oral antimuscarinic drugs prescribed for OAB, across different age groups.OBJECTIVES• To describe the level of persistence for patients receiving antimuscarinics for overactive bladder (OAB) over a 12-month period based on real prescription data from the UK. • To investigate patterns of persistence with oral antimuscarinic drugs prescribed for OAB, across different age groups.• UK prescription data from a longitudinal patient database were analysed retrospectively to assess persistence with darifenacin, flavoxate, oxybutynin (extended release [ER] and immediate release [IR]), propiverine, solifenacin, tolterodine (ER/IR) and trospium. • Data were extracted from the medical records of >1,200,000 registered patients via general practice software, and anonymized prescription data were collated for all eligible patients with documented OAB (n = 4833). • Data were collected on patients who started treatment between January 2007 and December 2007 and were collected up to December 2008, to allow each patient a full 12-month potential treatment period. Failure of persistence was declared after a gap of at least 1.5 times the length of the period of the most recent prescription. • The analysis included only patients who were new to a course of treatment (i.e. who had not been prescribed that particular treatment or dosage for at least 6 months before the study period).PATIENTS AND METHODS• UK prescription data from a longitudinal patient database were analysed retrospectively to assess persistence with darifenacin, flavoxate, oxybutynin (extended release [ER] and immediate release [IR]), propiverine, solifenacin, tolterodine (ER/IR) and trospium. • Data were extracted from the medical records of >1,200,000 registered patients via general practice software, and anonymized prescription data were collated for all eligible patients with documented OAB (n = 4833). • Data were collected on patients who started treatment between January 2007 and December 2007 and were collected up to December 2008, to allow each patient a full 12-month potential treatment period. Failure of persistence was declared after a gap of at least 1.5 times the length of the period of the most recent prescription. • The analysis included only patients who were new to a course of treatment (i.e. who had not been prescribed that particular treatment or dosage for at least 6 months before the study period).• The number of patients prescribed each antimuscarinic drug varied from 23 for darifenacin to 1758 for tolterodine ER. • The longest mean persistence was reported for solifenacin (187 days versus 77-157 days for the other treatments). • At 3 months, the proportions of patients still on their original treatment were: solifenacin 58%, darifenacin 52%, tolterodine ER 47%, propiverine 47%, tolterodine IR 46%, oxybutynin ER 44%, trospium 42%, oxybutynin IR 40%, flavoxate 28%. • At 12 months, the proportions of patients still on their original treatment were: solifenacin 35%, tolterodine ER 28%, propiverine 27%, oxybutynin ER 26%, trospium 26%, tolterodine IR 24%, oxybutynin IR 22%, darifenacin 17%, flavoxate 14%. • In a sub-analysis stratified by age, patients aged ≥ 60 years were more likely to persist with prescribed therapy over the 12-month period than those aged <60 years.RESULTS• The number of patients prescribed each antimuscarinic drug varied from 23 for darifenacin to 1758 for tolterodine ER. • The longest mean persistence was reported for solifenacin (187 days versus 77-157 days for the other treatments). • At 3 months, the proportions of patients still on their original treatment were: solifenacin 58%, darifenacin 52%, tolterodine ER 47%, propiverine 47%, tolterodine IR 46%, oxybutynin ER 44%, trospium 42%, oxybutynin IR 40%, flavoxate 28%. • At 12 months, the proportions of patients still on their original treatment were: solifenacin 35%, tolterodine ER 28%, propiverine 27%, oxybutynin ER 26%, trospium 26%, tolterodine IR 24%, oxybutynin IR 22%, darifenacin 17%, flavoxate 14%. • In a sub-analysis stratified by age, patients aged ≥ 60 years were more likely to persist with prescribed therapy over the 12-month period than those aged <60 years.• Twelve months after the initial prescription, persistence rates with pharmacotherapy in the context of OAB are generally low. • Solifenacin was associated with higher levels of persistence compared with other prescribed antimuscarinic agents. • Older people are more likely than younger patients to persist with prescribed therapy. Further studies are required to understand this finding and why patients are more likely to persist with one drug rather than another.CONCLUSIONS• Twelve months after the initial prescription, persistence rates with pharmacotherapy in the context of OAB are generally low. • Solifenacin was associated with higher levels of persistence compared with other prescribed antimuscarinic agents. • Older people are more likely than younger patients to persist with prescribed therapy. Further studies are required to understand this finding and why patients are more likely to persist with one drug rather than another.
Study Type – Therapy (prevalence) Level of Evidence 2b What's known on the subject? and What does the study add? Persistence with long‐term medication in chronic diseases is typically low and that for overactive bladder medication is lower than average. Sub‐optimal persistence is a major challenge for the successful management of overactive bladder. Using UK prescription data, persistence was generally low across the range of antimuscarinics. Patients aged 60 years and above were more likely to persist with prescribed oral antimuscarinic drugs than younger patients (40–59 years). Solifenacin was consistently associated with the highest rate of persistence compared with the other antimuscarinics included in the study OBJECTIVES •  To describe the level of persistence for patients receiving antimuscarinics for overactive bladder (OAB) over a 12‐month period based on real prescription data from the UK. •  To investigate patterns of persistence with oral antimuscarinic drugs prescribed for OAB, across different age groups. PATIENTS AND METHODS •  UK prescription data from a longitudinal patient database were analysed retrospectively to assess persistence with darifenacin, flavoxate, oxybutynin (extended release [ER] and immediate release [IR]), propiverine, solifenacin, tolterodine (ER/IR) and trospium. •  Data were extracted from the medical records of >1 200 000 registered patients via general practice software, and anonymized prescription data were collated for all eligible patients with documented OAB (n= 4833). •  Data were collected on patients who started treatment between January 2007 and December 2007 and were collected up to December 2008, to allow each patient a full 12‐month potential treatment period. Failure of persistence was declared after a gap of at least 1.5 times the length of the period of the most recent prescription. •  The analysis included only patients who were new to a course of treatment (i.e. who had not been prescribed that particular treatment or dosage for at least 6 months before the study period). RESULTS •  The number of patients prescribed each antimuscarinic drug varied from 23 for darifenacin to 1758 for tolterodine ER. •  The longest mean persistence was reported for solifenacin (187 days versus 77−157 days for the other treatments). •  At 3 months, the proportions of patients still on their original treatment were: solifenacin 58%, darifenacin 52%, tolterodine ER 47%, propiverine 47%, tolterodine IR 46%, oxybutynin ER 44%, trospium 42%, oxybutynin IR 40%, flavoxate 28%. •  At 12 months, the proportions of patients still on their original treatment were: solifenacin 35%, tolterodine ER 28%, propiverine 27%, oxybutynin ER 26%, trospium 26%, tolterodine IR 24%, oxybutynin IR 22%, darifenacin 17%, flavoxate 14%. •  In a sub‐analysis stratified by age, patients aged ≥60 years were more likely to persist with prescribed therapy over the 12‐month period than those aged <60 years. CONCLUSIONS •  Twelve months after the initial prescription, persistence rates with pharmacotherapy in the context of OAB are generally low. •  Solifenacin was associated with higher levels of persistence compared with other prescribed antimuscarinic agents. •  Older people are more likely than younger patients to persist with prescribed therapy. Further studies are required to understand this finding and why patients are more likely to persist with one drug rather than another.
Study Type - Therapy (prevalence) Level of Evidence 2b What's known on the subject? and What does the study add? Persistence with long-term medication in chronic diseases is typically low and that for overactive bladder medication is lower than average. Sub-optimal persistence is a major challenge for the successful management of overactive bladder. Using UK prescription data, persistence was generally low across the range of antimuscarinics. Patients aged 60 years and above were more likely to persist with prescribed oral antimuscarinic drugs than younger patients (40-59 years). Solifenacin was consistently associated with the highest rate of persistence compared with the other antimuscarinics included in the study OBJECTIVES * To describe the level of persistence for patients receiving antimuscarinics for overactive bladder (OAB) over a 12-month period based on real prescription data from the UK. * To investigate patterns of persistence with oral antimuscarinic drugs prescribed for OAB, across different age groups. PATIENTS AND METHODS * UK prescription data from a longitudinal patient database were analysed retrospectively to assess persistence with darifenacin, flavoxate, oxybutynin (extended release [ER] and immediate release [IR]), propiverine, solifenacin, tolterodine (ER/IR) and trospium. * Data were extracted from the medical records of >1 200 000 registered patients via general practice software, and anonymized prescription data were collated for all eligible patients with documented OAB (n= 4833). * Data were collected on patients who started treatment between January 2007 and December 2007 and were collected up to December 2008, to allow each patient a full 12-month potential treatment period. Failure of persistence was declared after a gap of at least 1.5 times the length of the period of the most recent prescription. * The analysis included only patients who were new to a course of treatment (i.e. who had not been prescribed that particular treatment or dosage for at least 6 months before the study period). RESULTS * The number of patients prescribed each antimuscarinic drug varied from 23 for darifenacin to 1758 for tolterodine ER. * The longest mean persistence was reported for solifenacin (187 days versus 77-157 days for the other treatments). * At 3 months, the proportions of patients still on their original treatment were: solifenacin 58%, darifenacin 52%, tolterodine ER 47%, propiverine 47%, tolterodine IR 46%, oxybutynin ER 44%, trospium 42%, oxybutynin IR 40%, flavoxate 28%. * At 12 months, the proportions of patients still on their original treatment were: solifenacin 35%, tolterodine ER 28%, propiverine 27%, oxybutynin ER 26%, trospium 26%, tolterodine IR 24%, oxybutynin IR 22%, darifenacin 17%, flavoxate 14%. * In a sub-analysis stratified by age, patients aged ≥60 years were more likely to persist with prescribed therapy over the 12-month period than those aged <60 years. CONCLUSIONS * Twelve months after the initial prescription, persistence rates with pharmacotherapy in the context of OAB are generally low. * Solifenacin was associated with higher levels of persistence compared with other prescribed antimuscarinic agents. * Older people are more likely than younger patients to persist with prescribed therapy. Further studies are required to understand this finding and why patients are more likely to persist with one drug rather than another.
Author Compion, Gerhard
Fahey, Amanda
Siddiqui, Emad
Wagg, Adrian
Author_xml – sequence: 1
  givenname: Adrian
  surname: Wagg
  fullname: Wagg, Adrian
– sequence: 2
  givenname: Gerhard
  surname: Compion
  fullname: Compion, Gerhard
– sequence: 3
  givenname: Amanda
  surname: Fahey
  fullname: Fahey, Amanda
– sequence: 4
  givenname: Emad
  surname: Siddiqui
  fullname: Siddiqui, Emad
BackLink http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26710543$$DView record in Pascal Francis
https://www.ncbi.nlm.nih.gov/pubmed/22409769$$D View this record in MEDLINE/PubMed
BookMark eNqNkVuLFDEQhYOsuBf9CxIQwZcZc5t0tw-CLu4d9MEB8SVUJxU2Q093m3Tvzvx707szCvu0eUlx8tWpUOeYHLRdi4RQzuY8n4-rOVdazRRnv-aCcZFVJuR884Ic_Xs42Nes0ofkOKUVY1nQi1fkUIisFro6Ir9_YEwhDdhapPdhuKV9xGRjqNFRaIewHpOFGNpg6XCLEfot9V2k3V2u7RDukNYNOIfxEwW6vKa46TGGye41eemhSfhmd5-Q5dm3n6cXs5vv55enX25mVolSzlzJalkiB8FVUXj0QgNXtfMoQSsGQkCt3YJJhLp0zlW8LiuvhPC4qDiCPCEfHn372P0ZMQ1mHZLFpoEWuzEZLmTBKl6VZUbfPUFX3Rjb_DvDC11UWkheZertjhrrNTrTx7CGuDX7rWXg_Q6AvJzGR2htSP85XXC2UDJznx85G7uUInpjwwBD6NohQmgMZ2aK06zMlJSZUjNTnOYhTrPJBuUTg_2MZ7TuZt-HBrfP7jNfr5YPpfwLTCm3Ng
CODEN BJINFO
CitedBy_id crossref_primary_10_1097_MOU_0000000000000108
crossref_primary_10_1111_luts_12088
crossref_primary_10_1002_nau_22383
crossref_primary_10_1016_j_juro_2013_08_082
crossref_primary_10_1080_13696998_2016_1204307
crossref_primary_10_1002_nau_22943
crossref_primary_10_1080_14737167_2016_1203258
crossref_primary_10_1007_s40272_017_0249_x
crossref_primary_10_1111_ijcp_12447
crossref_primary_10_1016_j_juro_2014_11_094
crossref_primary_10_1002_nau_22707
crossref_primary_10_1007_s00192_017_3492_3
crossref_primary_10_2147_IJWH_S372597
crossref_primary_10_1007_s00210_012_0821_4
crossref_primary_10_1111_iju_13498
crossref_primary_10_1111_luts_12417
crossref_primary_10_1080_03007995_2021_1885366
crossref_primary_10_3834_uij_1944_5784_2013_12_02
crossref_primary_10_3389_fphar_2021_756582
crossref_primary_10_1080_17512433_2017_1275570
crossref_primary_10_1007_s11255_018_1869_y
crossref_primary_10_1016_j_aju_2015_07_003
crossref_primary_10_1111_ijcp_12693
crossref_primary_10_18553_jmcp_2018_24_1_65
crossref_primary_10_1111_bju_12006
crossref_primary_10_1002_nau_23256
crossref_primary_10_1080_14740338_2018_1453496
crossref_primary_10_1111_luts_12188
crossref_primary_10_1007_s00192_019_04193_4
crossref_primary_10_1186_s12894_017_0216_4
crossref_primary_10_1002_nau_22603
crossref_primary_10_1111_ijcp_12783
crossref_primary_10_1016_j_archger_2018_09_005
crossref_primary_10_1038_nrurol_2015_183
crossref_primary_10_1177_2051415817706045
crossref_primary_10_1016_j_acuro_2013_05_003
crossref_primary_10_1080_03007995_2017_1419170
crossref_primary_10_1371_journal_pone_0147137
crossref_primary_10_1007_s11934_012_0262_0
crossref_primary_10_1177_1756287215591763
crossref_primary_10_4111_icu_2017_58_2_109
crossref_primary_10_5213_inj_1632520_260
crossref_primary_10_1016_j_eururo_2013_11_010
crossref_primary_10_1080_14656566_2022_2126311
crossref_primary_10_1111_iju_15530
crossref_primary_10_1016_j_semerg_2016_05_006
crossref_primary_10_1136_bmjopen_2013_003297
crossref_primary_10_1007_s00345_014_1244_2
crossref_primary_10_1111_ijcp_12433
crossref_primary_10_12968_bjon_2020_29_18_S30
crossref_primary_10_1517_14728214_2013_823156
crossref_primary_10_1016_j_eururo_2017_11_002
crossref_primary_10_1590_S1677_5538_IBJU_2013_04_09
crossref_primary_10_1186_s12916_017_0828_2
crossref_primary_10_1016_j_mpmed_2016_10_001
crossref_primary_10_1111_ijcp_13616
crossref_primary_10_1016_j_maturitas_2019_04_216
crossref_primary_10_1186_s12894_021_00881_w
crossref_primary_10_1002_nau_23315
crossref_primary_10_1016_j_euf_2023_09_017
crossref_primary_10_1111_ans_19309
crossref_primary_10_1111_iju_13174
crossref_primary_10_1002_nau_25040
crossref_primary_10_1111_luts_12459
crossref_primary_10_1002_nau_24079
crossref_primary_10_1111_bju_13882
crossref_primary_10_1517_14656566_2013_796930
crossref_primary_10_3389_fphys_2025_1534517
crossref_primary_10_1016_j_eururo_2012_10_016
crossref_primary_10_1186_1471_2490_13_45
crossref_primary_10_1177_1756287215614237
crossref_primary_10_2217_cpr_14_38
crossref_primary_10_1097_CU9_0000000000000037
crossref_primary_10_1016_j_ejogrb_2016_12_030
crossref_primary_10_1007_s11255_021_02802_0
crossref_primary_10_3390_molecules25061384
crossref_primary_10_1007_s11884_019_00501_2
crossref_primary_10_1080_21681805_2019_1619832
crossref_primary_10_1111_jog_13541
crossref_primary_10_1016_j_cct_2016_09_005
crossref_primary_10_3390_ph17010116
crossref_primary_10_1016_j_maturitas_2013_07_003
crossref_primary_10_1080_14656566_2016_1186645
crossref_primary_10_1097_MBP_0000000000000320
crossref_primary_10_1007_s00120_014_3629_7
crossref_primary_10_2217_WHE_15_31
crossref_primary_10_1016_j_acuroe_2013_03_002
crossref_primary_10_1016_j_urology_2019_06_002
crossref_primary_10_1093_ageing_aft214
crossref_primary_10_1177_1756287217702797
crossref_primary_10_1016_j_urols_2017_05_006
crossref_primary_10_1186_s12894_017_0226_2
crossref_primary_10_1111_bju_15040
crossref_primary_10_1136_dtb_2013_8_0196
crossref_primary_10_1111_ijcp_12996
crossref_primary_10_1007_s40266_013_0145_1
crossref_primary_10_1016_j_jgyn_2014_06_011
crossref_primary_10_1080_14656566_2023_2264183
crossref_primary_10_1097_SPV_0000000000000215
crossref_primary_10_1111_ijcp_12194
crossref_primary_10_1186_s12913_020_05315_1
crossref_primary_10_5317_wjog_v2_i4_65
crossref_primary_10_1016_j_eurger_2017_04_002
crossref_primary_10_1016_j_semerg_2015_10_006
crossref_primary_10_1111_iju_13422
crossref_primary_10_1177_2042098616659412
crossref_primary_10_1007_s11136_015_1216_z
crossref_primary_10_1111_luts_12247
crossref_primary_10_1002_nau_23993
crossref_primary_10_1185_03007995_2014_968704
crossref_primary_10_1002_nau_22780
crossref_primary_10_1007_s11934_013_0335_8
crossref_primary_10_1002_nau_22544
crossref_primary_10_1007_s12325_024_03019_0
crossref_primary_10_1016_j_purol_2013_09_020
crossref_primary_10_1097_SPV_0000000000000744
crossref_primary_10_1248_cpb_c19_00552
crossref_primary_10_1177_1756287215589250
crossref_primary_10_1517_13543784_2014_925877
crossref_primary_10_1038_s41598_018_27617_5
crossref_primary_10_1517_13543784_2015_1076390
crossref_primary_10_2147_IJWH_S369588
crossref_primary_10_1016_j_jfma_2018_05_006
crossref_primary_10_1007_s00129_017_4031_5
crossref_primary_10_1002_nau_23980
crossref_primary_10_2174_1389450121666200716202103
crossref_primary_10_1111_bju_13162
crossref_primary_10_1111_luts_12253
crossref_primary_10_1111_luts_12382
crossref_primary_10_1111_luts_12141
crossref_primary_10_1186_s12894_018_0390_z
crossref_primary_10_1111_jog_14708
crossref_primary_10_1016_j_juro_2013_10_046
crossref_primary_10_1111_iju_13764
crossref_primary_10_1517_14656566_2014_898752
crossref_primary_10_1016_j_acuroe_2015_09_008
crossref_primary_10_2217_WHE_14_1
crossref_primary_10_12688_f1000research_7131_1
crossref_primary_10_1002_nau_24741
crossref_primary_10_1007_s11255_018_1907_9
crossref_primary_10_1002_nau_23774
crossref_primary_10_1111_ijcp_12824
crossref_primary_10_1002_nau_25397
crossref_primary_10_1007_s11934_015_0531_9
crossref_primary_10_1517_14656566_2016_1145662
crossref_primary_10_1002_nau_23413
crossref_primary_10_1517_17460441_2014_892923
crossref_primary_10_1159_000507230
crossref_primary_10_3390_toxins15010030
crossref_primary_10_1002_nau_22795
crossref_primary_10_1111_luts_12474
crossref_primary_10_1007_s00192_021_04785_z
crossref_primary_10_1177_17562872211039034
crossref_primary_10_1016_j_ejogrb_2018_01_002
crossref_primary_10_1007_s11884_014_0247_6
crossref_primary_10_1016_j_eururo_2017_01_037
crossref_primary_10_1517_13543784_2015_1001836
crossref_primary_10_1186_s12877_017_0690_2
crossref_primary_10_3111_13696998_2014_995300
crossref_primary_10_1016_j_acuro_2013_03_005
crossref_primary_10_1016_j_maturitas_2014_08_009
crossref_primary_10_1038_s41598_020_60967_7
crossref_primary_10_1111_bju_12649
crossref_primary_10_1021_acs_jmedchem_5b00638
crossref_primary_10_1038_s41598_024_67326_w
crossref_primary_10_1021_acs_jproteome_7b00568
crossref_primary_10_1186_s12894_018_0376_x
crossref_primary_10_1080_20016689_2018_1438721
crossref_primary_10_1007_s40261_014_0240_z
crossref_primary_10_1016_j_surge_2022_09_004
crossref_primary_10_3109_13697137_2014_947257
crossref_primary_10_1002_nau_23276
crossref_primary_10_1016_j_jval_2015_05_011
crossref_primary_10_1016_j_urology_2015_01_002
crossref_primary_10_1016_j_acuro_2015_09_004
crossref_primary_10_1002_nau_22505
crossref_primary_10_1073_pnas_1901655116
crossref_primary_10_1111_iju_13218
crossref_primary_10_1007_s00192_014_2585_5
crossref_primary_10_1177_2053369120927112
crossref_primary_10_1517_14740338_2016_1165663
crossref_primary_10_1177_1756287217742837
crossref_primary_10_1016_j_tcmj_2015_12_003
crossref_primary_10_1002_nau_23944
crossref_primary_10_1002_nau_22978
crossref_primary_10_1038_nrurol_2017_67
crossref_primary_10_1124_pharmrev_121_000523
crossref_primary_10_3111_13696998_2014_941066
crossref_primary_10_1097_SPV_0000000000000277
crossref_primary_10_1177_0391560319859785
crossref_primary_10_1016_j_eururo_2017_03_040
crossref_primary_10_1016_j_maturitas_2013_01_012
crossref_primary_10_1080_14656566_2023_2237406
crossref_primary_10_1188_15_S1_CJON_6_30
crossref_primary_10_1002_nau_23050
crossref_primary_10_1111_iju_12355
crossref_primary_10_1111_bju_15555
crossref_primary_10_4103_UROS_UROS_2_18
crossref_primary_10_1186_s12906_018_2101_4
crossref_primary_10_1002_nau_24824
crossref_primary_10_1111_luts_12153
crossref_primary_10_1002_nau_23974
crossref_primary_10_1002_nau_23852
crossref_primary_10_1097_AOG_0000000000003320
crossref_primary_10_1111_luts_12391
crossref_primary_10_1111_ggi_13465
crossref_primary_10_1111_iju_13558
crossref_primary_10_1007_s11255_020_02412_2
crossref_primary_10_1038_s41598_022_23795_5
crossref_primary_10_1371_journal_pone_0204456
crossref_primary_10_1111_bju_13945
crossref_primary_10_1097_GME_0000000000000730
crossref_primary_10_1111_bju_12730
crossref_primary_10_4111_icu_2016_57_2_84
crossref_primary_10_1016_j_euf_2018_03_011
crossref_primary_10_1007_s00192_016_2945_4
crossref_primary_10_1016_j_jns_2017_11_028
crossref_primary_10_1007_s00192_016_3118_1
crossref_primary_10_1186_s12894_015_0031_8
crossref_primary_10_1016_j_eururo_2012_08_060
crossref_primary_10_1038_nrurol_2013_143
crossref_primary_10_1016_j_purol_2015_01_006
crossref_primary_10_1111_ijun_12058
crossref_primary_10_1136_bmjopen_2018_021889
crossref_primary_10_1016_j_purol_2013_02_001
crossref_primary_10_1021_acs_jmedchem_6b01197
crossref_primary_10_1016_j_acuroe_2013_05_005
crossref_primary_10_1016_j_ejogrb_2017_01_028
crossref_primary_10_1055_s_0043_1770093
crossref_primary_10_1097_MD_0000000000032052
crossref_primary_10_1093_ageing_afu017
Cites_doi 10.1016/S0149-2918(02)85137-2
10.1016/j.juro.2009.11.026
10.1111/j.1751-7176.2010.00356.x
10.1111/j.1524-4733.2005.00041.x
10.1111/j.1742-1241.2006.01059.x
10.1056/NEJMra032662
10.1016/j.bone.2005.10.022
10.18553/jmcp.2008.14.3.291
10.1007/s00228-010-0917-z
10.1016/j.urology.2010.03.097
10.1001/jama.285.4.437
10.1002/nau.20737
10.18553/jmcp.2009.15.9.728
10.1136/bmj.39553.670231.25
10.1111/j.1464-410X.2006.06035.x
10.1111/j.1524-4733.2007.00213.x
10.1007/s00228-008-0600-9
10.1046/j.1464-410x.2001.02228.x
10.1038/nrurol.2010.147
10.1016/S0002-9343(03)00362-0
10.3410/M2-9
10.1111/j.1464-410X.2009.09036.x
10.1111/j.1471-0528.1997.tb12054.x
10.1111/j.1464-410X.2009.09035.x
10.1016/j.urology.2010.07.275
10.1097/01.hjh.0000186832.41125.8a
10.1016/S0090-4295(99)00492-6
10.1111/j.1368-5031.2005.00617.x
10.1007/BF02850081
10.1111/j.1464-410X.2004.05255.x
10.1111/j.1464-410X.2008.07769.x
10.1016/j.eururo.2004.11.004
10.1111/j.1742-1241.2010.02626.x
10.1007/s00198-009-0930-1
ContentType Journal Article
Copyright 2012 THE AUTHORS. BJU INTERNATIONAL © 2012 BJU INTERNATIONAL
2014 INIST-CNRS
2012 THE AUTHORS. BJU INTERNATIONAL © 2012 BJU INTERNATIONAL.
BJUI © 2012 BJU International
Copyright_xml – notice: 2012 THE AUTHORS. BJU INTERNATIONAL © 2012 BJU INTERNATIONAL
– notice: 2014 INIST-CNRS
– notice: 2012 THE AUTHORS. BJU INTERNATIONAL © 2012 BJU INTERNATIONAL.
– notice: BJUI © 2012 BJU International
DBID AAYXX
CITATION
IQODW
CGR
CUY
CVF
ECM
EIF
NPM
7QP
7X8
DOI 10.1111/j.1464-410X.2012.11023.x
DatabaseName CrossRef
Pascal-Francis
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
Calcium & Calcified Tissue Abstracts
MEDLINE - Academic
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Calcium & Calcified Tissue Abstracts
MEDLINE - Academic
DatabaseTitleList MEDLINE
MEDLINE - Academic

Calcium & Calcified Tissue Abstracts
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 1464-410X
EndPage 1774
ExternalDocumentID 3963137161
22409769
26710543
10_1111_j_1464_410X_2012_11023_x
BJU11023
Genre article
Research Support, Non-U.S. Gov't
Journal Article
GeographicLocations United Kingdom
Europe
GroupedDBID ---
.3N
.55
.GA
.Y3
05W
0R~
10A
1OC
23N
24P
2WC
31~
33P
36B
3O-
3SF
4.4
50Y
50Z
51W
51X
52M
52N
52O
52P
52R
52S
52T
52U
52V
52W
52X
53G
5GY
5HH
5LA
5RE
5VS
66C
6P2
702
7PT
8-0
8-1
8-3
8-4
8-5
8UM
930
A01
A03
AAESR
AAEVG
AAHHS
AAHQN
AAIPD
AAMNL
AANLZ
AAONW
AASGY
AAXRX
AAYCA
AAZKR
ABCQN
ABCUV
ABDBF
ABEML
ABJNI
ABLJU
ABOCM
ABPVW
ABQWH
ABXGK
ACAHQ
ACCFJ
ACCZN
ACFBH
ACGFS
ACGOF
ACMXC
ACPOU
ACPRK
ACSCC
ACUHS
ACXBN
ACXQS
ADBBV
ADBTR
ADEOM
ADIZJ
ADKYN
ADMGS
ADOZA
ADXAS
ADZMN
ADZOD
AEEZP
AEIGN
AEIMD
AENEX
AEQDE
AEUQT
AEUYR
AFBPY
AFEBI
AFFNX
AFFPM
AFGKR
AFPWT
AFWVQ
AFZJQ
AHBTC
AHMBA
AIACR
AITYG
AIURR
AIWBW
AJBDE
ALAGY
ALMA_UNASSIGNED_HOLDINGS
ALUQN
ALVPJ
AMBMR
AMYDB
ATUGU
AZBYB
AZVAB
BAFTC
BAWUL
BFHJK
BHBCM
BMXJE
BROTX
BRXPI
BY8
C45
CAG
COF
CS3
D-6
D-7
D-E
D-F
DCZOG
DIK
DPXWK
DR2
DRFUL
DRMAN
DRSTM
DU5
E3Z
EAD
EAP
EBC
EBD
EBS
EJD
EMB
EMK
EMOBN
ESX
EX3
F00
F01
F04
F5P
FUBAC
G-S
G.N
GODZA
H.X
HF~
HGLYW
HZI
HZ~
IHE
IX1
J0M
J5H
K48
KBYEO
LATKE
LC2
LC3
LEEKS
LH4
LITHE
LOXES
LP6
LP7
LUTES
LW6
LYRES
MEWTI
MK4
MRFUL
MRMAN
MRSTM
MSFUL
MSMAN
MSSTM
MXFUL
MXMAN
MXSTM
N04
N05
N9A
NF~
O66
O9-
OIG
OK1
OVD
P2P
P2W
P2X
P2Z
P4B
P4D
PQQKQ
Q.N
Q11
QB0
R.K
RJQFR
ROL
RX1
SUPJJ
SV3
TEORI
TUS
UB1
V9Y
W8V
W99
WBKPD
WHWMO
WIH
WIJ
WIK
WOHZO
WOW
WQJ
WRC
WVDHM
WXI
WXSBR
X7M
XG1
YFH
ZGI
ZXP
~IA
~WT
AAYXX
AEYWJ
AGHNM
AGYGG
CITATION
AAMMB
AEFGJ
AGXDD
AIDQK
AIDYY
IQODW
CGR
CUY
CVF
ECM
EIF
NPM
7QP
7X8
ID FETCH-LOGICAL-c4283-d80b38e1a21477fef26a14bdfe3a640a22ab6d503eab8ddd91b89f422fe591ea3
IEDL.DBID DR2
ISSN 1464-4096
1464-410X
IngestDate Fri Jul 11 09:06:45 EDT 2025
Fri Jul 25 04:23:40 EDT 2025
Mon Jul 21 06:02:24 EDT 2025
Mon Jul 21 09:17:31 EDT 2025
Thu Apr 24 23:08:19 EDT 2025
Tue Jul 01 03:49:55 EDT 2025
Wed Jan 22 16:38:00 EST 2025
IsPeerReviewed true
IsScholarly true
Issue 11
Keywords Drug
Nephrology
Urinary system disease
Urinary tract disease
Urology
Persistence
Anticholinergic agent
Cholinergic receptor
Treatment
Solifenacin
Antimuscarinic agent
Overactive bladder
Bladder disease
Muscarinic receptor
Antagonist
antimuscarinic drugs
Language English
License CC BY 4.0
2012 THE AUTHORS. BJU INTERNATIONAL © 2012 BJU INTERNATIONAL.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c4283-d80b38e1a21477fef26a14bdfe3a640a22ab6d503eab8ddd91b89f422fe591ea3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
PMID 22409769
PQID 1767962319
PQPubID 1026371
PageCount 8
ParticipantIDs proquest_miscellaneous_1237091988
proquest_journals_1767962319
pubmed_primary_22409769
pascalfrancis_primary_26710543
crossref_citationtrail_10_1111_j_1464_410X_2012_11023_x
crossref_primary_10_1111_j_1464_410X_2012_11023_x
wiley_primary_10_1111_j_1464_410X_2012_11023_x_BJU11023
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate December 2012
PublicationDateYYYYMMDD 2012-12-01
PublicationDate_xml – month: 12
  year: 2012
  text: December 2012
PublicationDecade 2010
PublicationPlace Oxford, UK
PublicationPlace_xml – name: Oxford, UK
– name: Oxford
– name: England
– name: Edgecliff
PublicationTitle BJU international
PublicationTitleAlternate BJU Int
PublicationYear 2012
Publisher Blackwell Publishing Ltd
Wiley-Blackwell
Wiley Subscription Services, Inc
Publisher_xml – name: Blackwell Publishing Ltd
– name: Wiley-Blackwell
– name: Wiley Subscription Services, Inc
References 2010; 12
2010; 76
2006; 97
2001; 285
2009; 65
2000; 6
2010; 105
2010
2006; 38
2009
2008; 14
2006
2010; 183
2008; 11
2003
2008; 102
2003; 115
2005; 22
2005; 23
2009; 28
2001; 87
2005; 47
2006; 60
1997; 104
2010; 21
2001; 7
2004; 350
2000; 55
2002; 24
2005; 8
2005; 95
2011; 65
2008; 336
2011; 67
2005; 59
2010; 2
2010; 7
2003; 20
2005; 11
2009; 15
e_1_2_8_27_2
e_1_2_8_29_2
e_1_2_8_23_2
e_1_2_8_46_2
e_1_2_8_24_2
e_1_2_8_45_2
e_1_2_8_25_2
e_1_2_8_48_2
e_1_2_8_47_2
Brown JS (e_1_2_8_9_2) 2000; 6
Mullins CD (e_1_2_8_28_2) 2005; 11
e_1_2_8_2_2
e_1_2_8_4_2
e_1_2_8_3_2
e_1_2_8_6_2
e_1_2_8_5_2
e_1_2_8_8_2
e_1_2_8_7_2
e_1_2_8_42_2
e_1_2_8_20_2
e_1_2_8_41_2
e_1_2_8_44_2
e_1_2_8_22_2
e_1_2_8_43_2
e_1_2_8_40_2
e_1_2_8_16_2
Schabert VF (e_1_2_8_21_2) 2009; 15
e_1_2_8_39_2
e_1_2_8_17_2
e_1_2_8_38_2
Smith AL (e_1_2_8_11_2) 2010; 2
e_1_2_8_18_2
Nabi G (e_1_2_8_13_2) 2006
e_1_2_8_19_2
e_1_2_8_12_2
e_1_2_8_35_2
e_1_2_8_34_2
e_1_2_8_14_2
e_1_2_8_37_2
e_1_2_8_15_2
e_1_2_8_36_2
Shaya FT (e_1_2_8_26_2) 2005; 11
McGhan WF (e_1_2_8_10_2) 2001; 7
e_1_2_8_31_2
e_1_2_8_30_2
e_1_2_8_33_2
e_1_2_8_32_2
24029333 - J Urol. 2013 Oct;190(4):1328
References_xml – volume: 59
  start-page: 931
  year: 2005
  end-page: 7
  article-title: Persistence with antimuscarinic therapy in patients with overactive bladder
  publication-title: Int J Clin Pract
– year: 2009
– volume: 105
  start-page: 1276
  year: 2010
  end-page: 82
  article-title: Patient‐reported reasons for discontinuing overactive bladder medication
  publication-title: BJU Int
– volume: 115
  start-page: 209
  year: 2003
  end-page: 16
  article-title: Early discontinuation of treatment for osteoporosis
  publication-title: Am J Med
– volume: 6
  start-page: S574
  year: 2000
  end-page: 9
  article-title: Comorbidities associated with overactive bladder
  publication-title: Am J Manag Care
– volume: 15
  start-page: 728
  year: 2009
  end-page: 40
  article-title: Comparing adherence and persistence across 6 chronic medication classes
  publication-title: J Manag Care Pharm
– volume: 47
  start-page: 376
  year: 2005
  end-page: 84
  article-title: Long‐term open‐label solifenacin treatment associated with persistence with therapy in patients with overactive bladder syndrome
  publication-title: Eur Urol
– volume: 11
  start-page: 44
  year: 2008
  end-page: 7
  article-title: Medication compliance and persistence: terminology and definitions
  publication-title: Value Health
– volume: 76
  start-page: 1350
  year: 2010
  end-page: 7
  article-title: Efficacy and tolerability of fesoterodine in older and younger subjects with overactive bladder
  publication-title: Urology
– year: 2003
– volume: 105
  start-page: 1283
  year: 2010
  end-page: 90
  article-title: Predictors of discontinuing overactive bladder medications
  publication-title: BJU Int
– volume: 38
  start-page: 922
  year: 2006
  end-page: 8
  article-title: Assessment of compliance with osteoporosis treatment and its consequences in a managed care population
  publication-title: Bone
– volume: 11
  start-page: S121
  year: 2005
  end-page: 9
  article-title: Persistence with overactive bladder pharmacotherapy in a Medicaid population
  publication-title: Am J Manag Care
– volume: 65
  start-page: 309
  year: 2009
  end-page: 14
  article-title: Persistence of antimuscarinic drug use
  publication-title: Eur J Clin Pharmacol
– volume: 14
  start-page: 291
  year: 2008
  end-page: 301
  article-title: Persistence, adherence, and switch rates among extended‐release and immediate‐release overactive bladder medications in a regional managed care plan
  publication-title: J Manag Care Pharm
– volume: 12
  start-page: 757
  year: 2010
  end-page: 64
  article-title: ASH position paper: adherence and persistence with taking medication to control high blood pressure
  publication-title: J Clin Hypertens (Greenwich)
– volume: 15
  start-page: S118
  year: 2009
  end-page: 22
  article-title: Challenges for managing overactive bladder and guidance for patient support
  publication-title: Am J Manag Care
– volume: 336
  start-page: 1114
  year: 2008
  end-page: 7
  article-title: Adherence to prescribed antihypertensive drug treatments: longitudinal study of electronically compiled dosing histories
  publication-title: BMJ
– volume: 23
  start-page: 2093
  year: 2005
  end-page: 100
  article-title: Patterns of persistence with antihypertensive medications in newly diagnosed hypertensive patients in Italy: a retrospective cohort study in primary care
  publication-title: J Hypertens
– volume: 350
  start-page: 786
  year: 2004
  end-page: 99
  article-title: Management of overactive bladder
  publication-title: N Engl J Med
– year: 2010
– volume: 28
  start-page: 287
  year: 2009
  article-title: Reviewing the ICS 2002 terminology report: the ongoing debate
  publication-title: Neurourol Urodyn
– volume: 20
  start-page: 327
  year: 2003
  end-page: 36
  article-title: Prevalence and burden of overactive bladder in the United States
  publication-title: World J Urol
– start-page: CD003781
  issue: 4
  year: 2006
  article-title: Anticholinergic drugs versus placebo for overactive bladder syndrome in adults
  publication-title: Cochrane Database Syst Rev
– volume: 95
  start-page: 81
  year: 2005
  end-page: 5
  article-title: Improved quality of life in patients with overactive bladder symptoms treated with solifenacin
  publication-title: BJU Int
– volume: 8
  start-page: 495
  year: 2005
  end-page: 505
  article-title: Persistence and adherence of medications for chronic overactive bladder/urinary incontinence in the california medicaid program
  publication-title: Value Health
– volume: 104
  start-page: 988
  year: 1997
  end-page: 93
  article-title: A medium‐term analysis of the subjective efficacy of treatment for women with detrusor instability and low bladder compliance
  publication-title: Br J Obstet Gynaecol
– volume: 65
  start-page: 567
  year: 2011
  end-page: 85
  article-title: Persistence and adherence in the treatment of overactive bladder syndrome with anticholinergic therapy: a systematic review of the literature
  publication-title: Int J Clin Pract
– volume: 7
  start-page: S62
  year: 2001
  end-page: 75
  article-title: Cost effectiveness and quality of life considerations in the treatment of patients with overactive bladder
  publication-title: Am J Manag Care
– volume: 97
  start-page: 540
  year: 2006
  end-page: 6
  article-title: Time to onset of improvement in symptoms of overactive bladder using antimuscarinic treatment
  publication-title: BJU Int
– volume: 87
  start-page: 760
  year: 2001
  end-page: 6
  article-title: How widespread are the symptoms of an overactive bladder and how are they managed? A population‐based prevalence study
  publication-title: BJU Int
– volume: 60
  start-page: 896
  year: 2006
  end-page: 905
  article-title: Treatment persistence with once‐monthly ibandronate and patient support vs. once‐weekly alendronate: results from the PERSIST study
  publication-title: Int J Clin Pract
– start-page: 1
  end-page: 7
– volume: 22
  start-page: 313
  year: 2005
  end-page: 56
  article-title: Medication adherence and persistence: a comprehensive review
  publication-title: Adv Ther
– volume: 11
  start-page: S101
  year: 2005
  end-page: 2
  article-title: New perspectives on overactive bladder: quality of life impact, medication persistency, and treatment costs
  publication-title: Am J Manag Care
– volume: 183
  start-page: 1077
  year: 2010
  end-page: 81
  article-title: Overactive bladder medication adherence when medication is free to patients
  publication-title: J Urol
– volume: 67
  start-page: 535
  year: 2011
  end-page: 6
  article-title: Low persistence of anticholinergic drug use in Sweden
  publication-title: Eur J Clin Pharmacol
– volume: 21
  start-page: 145
  year: 2010
  end-page: 55
  article-title: Adherence to monthly and weekly oral bisphosphonates in women with osteoporosis
  publication-title: Osteoporos Int
– volume: 55
  start-page: 33
  year: 2000
  end-page: 46
  article-title: Muscarinic receptor antagonists in the treatment of overactive bladder
  publication-title: Urology
– volume: 2
  start-page: 9
  year: 2010
  article-title: Recent advances in management of bladder overactivity
  publication-title: F1000 Med Rep
– volume: 24
  start-page: 616
  year: 2002
  end-page: 28
  article-title: A multicenter, prospective, open‐label study of tolterodine extended‐release 4 mg for overactive bladder: the speed of onset of therapeutic assessment trial (STAT)
  publication-title: Clin Ther
– volume: 7
  start-page: 572
  year: 2010
  end-page: 82
  article-title: Management of overactive bladder
  publication-title: Nat Rev Urol
– volume: 285
  start-page: 437
  year: 2001
  end-page: 43
  article-title: Completeness of safety reporting in randomized trials: an evaluation of 7 medical areas
  publication-title: JAMA
– volume: 102
  start-page: 774
  year: 2008
  end-page: 9
  article-title: A review of adherence to drug therapy in patients with overactive bladder
  publication-title: BJU Int
– ident: e_1_2_8_15_2
  doi: 10.1016/S0149-2918(02)85137-2
– ident: e_1_2_8_27_2
  doi: 10.1016/j.juro.2009.11.026
– volume: 7
  start-page: S62
  year: 2001
  ident: e_1_2_8_10_2
  article-title: Cost effectiveness and quality of life considerations in the treatment of patients with overactive bladder
  publication-title: Am J Manag Care
– ident: e_1_2_8_19_2
  doi: 10.1111/j.1751-7176.2010.00356.x
– ident: e_1_2_8_22_2
  doi: 10.1111/j.1524-4733.2005.00041.x
– ident: e_1_2_8_24_2
– ident: e_1_2_8_48_2
  doi: 10.1111/j.1742-1241.2006.01059.x
– ident: e_1_2_8_8_2
  doi: 10.1056/NEJMra032662
– volume: 15
  start-page: S118
  year: 2009
  ident: e_1_2_8_21_2
  article-title: Challenges for managing overactive bladder and guidance for patient support
  publication-title: Am J Manag Care
– ident: e_1_2_8_38_2
  doi: 10.1016/j.bone.2005.10.022
– ident: e_1_2_8_43_2
– ident: e_1_2_8_46_2
– ident: e_1_2_8_17_2
  doi: 10.18553/jmcp.2008.14.3.291
– ident: e_1_2_8_35_2
  doi: 10.1007/s00228-010-0917-z
– ident: e_1_2_8_45_2
  doi: 10.1016/j.urology.2010.03.097
– ident: e_1_2_8_30_2
  doi: 10.1001/jama.285.4.437
– ident: e_1_2_8_3_2
  doi: 10.1002/nau.20737
– volume: 11
  start-page: S101
  year: 2005
  ident: e_1_2_8_28_2
  article-title: New perspectives on overactive bladder: quality of life impact, medication persistency, and treatment costs
  publication-title: Am J Manag Care
– ident: e_1_2_8_40_2
  doi: 10.18553/jmcp.2009.15.9.728
– ident: e_1_2_8_39_2
  doi: 10.1136/bmj.39553.670231.25
– ident: e_1_2_8_14_2
  doi: 10.1111/j.1464-410X.2006.06035.x
– ident: e_1_2_8_23_2
– ident: e_1_2_8_18_2
  doi: 10.1111/j.1524-4733.2007.00213.x
– ident: e_1_2_8_34_2
  doi: 10.1007/s00228-008-0600-9
– ident: e_1_2_8_6_2
  doi: 10.1046/j.1464-410x.2001.02228.x
– volume: 6
  start-page: S574
  year: 2000
  ident: e_1_2_8_9_2
  article-title: Comorbidities associated with overactive bladder
  publication-title: Am J Manag Care
– ident: e_1_2_8_2_2
  doi: 10.1038/nrurol.2010.147
– ident: e_1_2_8_36_2
  doi: 10.1016/S0002-9343(03)00362-0
– start-page: CD003781
  issue: 4
  year: 2006
  ident: e_1_2_8_13_2
  article-title: Anticholinergic drugs versus placebo for overactive bladder syndrome in adults
  publication-title: Cochrane Database Syst Rev
– volume: 2
  start-page: 9
  year: 2010
  ident: e_1_2_8_11_2
  article-title: Recent advances in management of bladder overactivity
  publication-title: F1000 Med Rep
  doi: 10.3410/M2-9
– ident: e_1_2_8_42_2
  doi: 10.1111/j.1464-410X.2009.09036.x
– ident: e_1_2_8_31_2
  doi: 10.1111/j.1471-0528.1997.tb12054.x
– ident: e_1_2_8_32_2
  doi: 10.1111/j.1464-410X.2009.09035.x
– volume: 11
  start-page: S121
  year: 2005
  ident: e_1_2_8_26_2
  article-title: Persistence with overactive bladder pharmacotherapy in a Medicaid population
  publication-title: Am J Manag Care
– ident: e_1_2_8_47_2
  doi: 10.1016/j.urology.2010.07.275
– ident: e_1_2_8_41_2
  doi: 10.1097/01.hjh.0000186832.41125.8a
– ident: e_1_2_8_12_2
  doi: 10.1016/S0090-4295(99)00492-6
– ident: e_1_2_8_4_2
  doi: 10.1111/j.1368-5031.2005.00617.x
– ident: e_1_2_8_7_2
– ident: e_1_2_8_20_2
  doi: 10.1007/BF02850081
– ident: e_1_2_8_29_2
  doi: 10.1111/j.1464-410X.2004.05255.x
– ident: e_1_2_8_25_2
  doi: 10.1111/j.1464-410X.2008.07769.x
– ident: e_1_2_8_16_2
  doi: 10.1016/j.eururo.2004.11.004
– ident: e_1_2_8_5_2
  doi: 10.1046/j.1464-410x.2001.02228.x
– ident: e_1_2_8_33_2
  doi: 10.1111/j.1742-1241.2010.02626.x
– ident: e_1_2_8_37_2
  doi: 10.1007/s00198-009-0930-1
– ident: e_1_2_8_44_2
– reference: 24029333 - J Urol. 2013 Oct;190(4):1328
SSID ssj0014665
Score 2.5254147
Snippet Study Type – Therapy (prevalence) Level of Evidence 2b What's known on the subject? and What does the study add? Persistence with long‐term medication in...
Study Type--Therapy (prevalence) Level of Evidence 2b. What's known on the subject? and What does the study add? Persistence with long-term medication in...
Study Type - Therapy (prevalence) Level of Evidence 2b What's known on the subject? and What does the study add? Persistence with long-term medication in...
SourceID proquest
pubmed
pascalfrancis
crossref
wiley
SourceType Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 1767
SubjectTerms Administration, Oral
Adult
Age Factors
antimuscarinic drugs
Biological and medical sciences
Bladder
Chronic Disease
Female
Humans
Longitudinal Studies
Male
Medical sciences
Medication Adherence - statistics & numerical data
Middle Aged
Muscarinic Antagonists - administration & dosage
Nephrology. Urinary tract diseases
overactive bladder
Patients
persistence
Prescription Drugs - administration & dosage
solifenacin
United Kingdom
Urinary Bladder, Overactive - drug therapy
Urinary incontinence
Urinary system involvement in other diseases. Miscellaneous
Urinary tract. Prostate gland
Title Persistence with prescribed antimuscarinic therapy for overactive bladder: a UK experience
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fj.1464-410X.2012.11023.x
https://www.ncbi.nlm.nih.gov/pubmed/22409769
https://www.proquest.com/docview/1767962319
https://www.proquest.com/docview/1237091988
Volume 110
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1LS8QwEA7iQQTx_VhfRPDapUnTNvWmooiiB3Fh8RKSJgFRd8XdBfXXO9N0KxUPIt5K2ylNMjP5mnz9hpBDFHCxXmeRS2EYhGM-kqVNI5FISJlFVjCNO7rXN9lFT1z2037Nf8J_YYI-RLPghpFR5WsMcG1G34NcRILFfWRocSS086SLeBKpW4iPbhslKbi1qioZTAC2t0k9Pz6oNVMtvOgRdJoP1S5-gqNtdFtNT-dL5HHasMBKeexOxqZbfnzTfPyfli-TxRrF0uPgditkxg1Wydx1vU-_Ru6RWI8OBC5FcamXIt8WEpRxlsJYPjxPoJ24eVTS8AfYOwX0TJFPqqsMTM0T5sTXI6pp74q6RpF5nfTOz-5OL6K6ikNUophbZGVsEumYxopIuXeeZ5oJY71LdCZizbk2mU3jxGkjrbUFM7LwgnPv0oI5nWyQ2cFw4LYIlQCPYKpl3JW5KEurufG5M-hUMeDYpEPy6YipspY4x0obT6r1qSMUdp3CrlNV16m3DmGN5UuQ-fiFzX7LKRpDngFsSwW8zu7US1SdGUaK5bhyB6i66JCD5jLENG7U6IEbTuAenuSA4wopO2QzeNfXwzkqlGVgnVc-8uvXVSeXvepw-8-WO2Qezwc2zy6ZHb9O3B5gsrHZr6LtE-TzJcQ
linkProvider Wiley-Blackwell
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1La9wwEB5KCm0h9J1m2zRVoFcvlizbcm9tHmyTbA4hC0svQrIkCNluQrILbX99Zyyvi0MOoeRmsEZY0szo82j0DcBnInBxwRSJz3EZpOchUbXLE5kpdJlVUXFDJ7rjk2I0kYfTfNqWA6K7MJEfogu4kWU0_poMnALSt61cJpKnU0rREpTRLrIhAsrHVOCbyhnsnXZcUti2qSsZZRC499N67uypt1etX5kbnLYQ613cBUj7-LbZoA5ewGw1tJiXcjFcLuyw_nOL9fGBxv4SnrdAln2NmvcKHvn5a3gybo_q38APyq0nHUKtYhTtZZRyiz7KesdwOc9_LnGgdH5Us3gJ7DdDAM0opdQ0TpjZGbnF6y_MsMkR8x0p81uYHOyf7Y6StpBDUhOfW-JUajPluaGiSGXwQRSGS-uCz0whUyOEsYXL08wbq5xzFbeqClKI4POKe5NtwNr8cu43gSlESLjbcuHrUta1M8KG0lvSqxShbDaAcrVkum5ZzqnYxkz3_nakpqnTNHW6mTr9awC8k7yKTB_3kNnuaUUnKApEbrnEz9laqYluncON5iUF7xBYVwPY6V6jWdNZjZn7yyW2EVmJUK5SagDvonr961wQSVmB0mWjJPf-XP3tcNI8vv9vyU_wdHQ2PtbH30-OPsAzahOTe7ZgbXG99B8Roi3sdmN6fwFB_Cne
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3faxQxEB6khSKI1t-ntUbwdY9NNpvN-qbWo7a2iHhw-BKSTQKl9Xq0d6D9653Z7K1s6UMR3xY2s2ySmcm3ybffALwlARcfrcpCidMgA4-ZbnyZyUJjyqxVzS2d6B4dq_2pPJiVs47_RP_CJH2IfsONIqPN1xTgCx-vB7nMJM9nxNASRGgXxRjx5KZUGDsEkL71UlLYti0rmWwQtw9ZPTc-abBU3VvYSxy1mMpd3IRHh_C2XZ8mD-B03bNESzkdr5Zu3FxdE338P13fhvsdjGXvk989hDth_gi2jrqD-sfwg5j15EHoU4z2ehkRbjFDueAZTubJzxX2k06PGpZ-AfvNED4zIpTaNgUzd0ZJ8eIds2x6yEIvyfwEppNP3z_uZ10Zh6whNbfM69wVOnBLJZGqGKJQlkvnYyiskrkVwjrly7wI1mnvfc2drqMUIoay5sEWT2Fjfj4Pz4FpxEe41nIRmko2jbfCxSo48qocgWwxgmo9Y6bpNM6p1MaZGXzrSENDZ2joTDt05tcIeG-5SDoft7DZHThFbygU4rZS4uvsrL3EdKnh0vCKtu4QVtcjeNPfxqCmkxo7D-crbCOKCoFcrfUIniXv-vtwQRJlCq2r1kdu_brmw8G0vXzxz5avYevr3sR8-Xx8-BLuUpPE7NmBjeXFKrxCfLZ0u23g_QGtMCiW
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Persistence+with+prescribed+antimuscarinic+therapy+for+overactive+bladder%3A+a+UK+experience&rft.jtitle=BJU+international&rft.au=Wagg%2C+Adrian&rft.au=Compion%2C+Gerhard&rft.au=Fahey%2C+Amanda&rft.au=Siddiqui%2C+Emad&rft.date=2012-12-01&rft.pub=Blackwell+Publishing+Ltd&rft.issn=1464-4096&rft.eissn=1464-410X&rft.volume=110&rft.issue=11&rft.spage=1767&rft.epage=1774&rft_id=info:doi/10.1111%2Fj.1464-410X.2012.11023.x&rft.externalDBID=10.1111%252Fj.1464-410X.2012.11023.x&rft.externalDocID=BJU11023
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1464-4096&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1464-4096&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1464-4096&client=summon