Advancing age within established Gleason score categories and the risk of prostate cancer‐specific mortality (PCSM)

• Published in: BJU international Vol. 110; no. 7; pp. 973 - 979
• Main Authors: Russo, Andrea L., Chen, Ming‐Hui, Aizer, Ayal A., Hattangadi, Jona A., D'Amico, Anthony V.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.10.2012; Wiley-Blackwell; Wiley Subscription Services, Inc
• Subjects: Adult; Age; Age Factors; Age of Onset; Aged; age‐related risk; Biological and medical sciences; Biopsy; Cause of Death; Confidence intervals; Gynecology. Andrology. Obstetrics; Humans; Male; Male genital diseases; Medical prognosis; Medical sciences; Middle Aged; Mortality; Neoplasm Grading; Nephrology. Urinary tract diseases; Prostate cancer; Prostate-Specific Antigen - metabolism; prostatic neoplasms; Prostatic Neoplasms - blood; Prostatic Neoplasms - mortality; Prostatic Neoplasms - pathology; Regression Analysis; Risk Factors; SEER programme; Tumors; Tumors of the urinary system; Urinary tract. Prostate gland; Histological grading; Gleason score; Prostate tumor; Nephrology; age-related risk; Urinary system disease; Prostate disease; Mortality; Malignant tumor; Risk analysis; Epidemiology; Urology; SEER programme; neoplasm grading; Anatomic pathology; Histopathology; Risk factor; prostatic neoplasms; Male genital diseases; Prostate cancer; Age; Cancer

Study Type – Prognosis (case series) Level of Evidence 4 What's known on the subject? and What does the study add? There is limited data that suggests that men aged >70 years have a higher proportion of Gleason 8–10 prostate cancer than men aged <70 years, as well as a higher risk of PSA...