Sucrose preference test: A systematic review of protocols for the assessment of anhedonia in rodents

• Published in: European neuropsychopharmacology Vol. 77; pp. 80 - 92
• Main Authors: Primo, Maria João, Fonseca-Rodrigues, Diana, Almeida, Armando, Teixeira, Pedro M., Pinto-Ribeiro, Filipa
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.12.2023
• Subjects: Anhedonia; Animals; Depressive Disorder, Major; Food; Major depressive disorder; Rodentia; Rodents; Sucrose; Sucrose preference test; Systematic review; Anhedonia; Systematic review; Sucrose preference test; Rodents; Major depressive disorder

Anhedonia is described as a decreased ability to experience rewarding and enjoyable activities, a core symptom of major depressive disorder. The sucrose preference test (SPT) is a widely used and reliable behavioural test to assess anhedonia in rodents, based on a two-bottle choice paradigm. To date...