A double-blind study evaluating the long-term safety of varenicline for smoking cessation

• Published in: Current medical research and opinion Vol. 23; no. 4; pp. 793 - 801
• Main Authors: Williams, Kathryn E., Reeves, Karen R., Billing, Clare B., Pennington, Ann M., Gong, Jason
• Format: Journal Article
• Language: English
• Published: England Informa UK Ltd 01.04.2007; Taylor & Francis; Informa Healthcare
• Subjects: Adolescent; Adult; Aged; Benzazepines - adverse effects; Benzazepines - therapeutic use; Double-Blind Method; Female; Humans; Long-term; Male; Middle Aged; Placebos; Point prevalence; Quinoxalines - adverse effects; Quinoxalines - therapeutic use; Randomized controlled trial; Safety; Smoking cessation; Smoking Cessation - methods; Smoking Prevention; Time; Time Factors; Treatment Outcome; Varenicline

ABSTRACT Objective: We assessed the safety of long-term varenicline administration for smoking cessation. Methods: In this randomized, double-blind, multicenter trial, eligible adult smokers (18–75 years) who smoked an average of ≥10 cigarettes/day were randomized to either varenicline 1 mg twice da...